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Delivery of an ectonucleotidase inhibitor with ROS-responsive nanoparticles overcomes adenosine-mediated cancer immunosuppression.

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Title: Delivery of an ectonucleotidase inhibitor with ROS-responsive nanoparticles overcomes adenosine-mediated cancer immunosuppression.
Authors: Mao C; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Yeh S; Department of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Fu J; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Porosnicu M; Depatment of Internal Medicine - Section of Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA., Thomas A; Depatment of Internal Medicine - Section of Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA., Kucera GL; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA., Votanopoulos KI; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.; Department of Surgery - Section of Surgical Oncology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Tian S; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Ming X; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Department of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
Source: Science translational medicine [Sci Transl Med] 2022 Jun 08; Vol. 14 (648), pp. eabh1261. Date of Electronic Publication: 2022 Jun 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Delivery of an ectonucleotidase inhibitor with ROS-responsive nanoparticles overcomes adenosine-mediated cancer immunosuppression.
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  Data: <searchLink fieldCode="AU" term="%22Mao+C%22">Mao C</searchLink>; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.<br /><searchLink fieldCode="AU" term="%22Yeh+S%22">Yeh S</searchLink>; Department of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.<br /><searchLink fieldCode="AU" term="%22Fu+J%22">Fu J</searchLink>; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.<br /><searchLink fieldCode="AU" term="%22Porosnicu+M%22">Porosnicu M</searchLink>; Depatment of Internal Medicine - Section of Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+A%22">Thomas A</searchLink>; Depatment of Internal Medicine - Section of Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.<br /><searchLink fieldCode="AU" term="%22Kucera+GL%22">Kucera GL</searchLink>; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.<br /><searchLink fieldCode="AU" term="%22Votanopoulos+KI%22">Votanopoulos KI</searchLink>; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.; Department of Surgery - Section of Surgical Oncology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.<br /><searchLink fieldCode="AU" term="%22Tian+S%22">Tian S</searchLink>; Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Ming+X%22">Ming X</searchLink>; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Department of Biomedical Engineering, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.; Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston-Salem, NC 27157, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2022 Jun 08; Vol. 14 (648), pp. eabh1261. <i>Date of Electronic Publication: </i>2022 Jun 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1126/scitranslmed.abh1261
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        Text: English
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            – D: 08
              M: 06
              Text: 2022 Jun 08
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              Y: 2022
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