(1 → 3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial.
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| Title: | (1 → 3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial. |
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| Authors: | Bloos F; Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany. frank.bloos@med.uni-jena.de.; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany. frank.bloos@med.uni-jena.de., Held J; Mikrobiologisches Institut-Klinische Mikrobiologie Immunologie und Hygiene, Universitätsklinikum Erlangen Und Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany., Kluge S; Department of Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Simon P; Department of Anesthesiology and Intensive Care Medicine, University of Leipzig Medical Centre, Leipzig, Germany.; Department of Anesthesiology and Surgical Intensive Care Medicine, University Hospital Augsburg, Augsburg, Germany., Kogelmann K; Department of Anesthesiology and Intensive Care Medicine, Hospital Emden, Emden, Germany., de Heer G; Department of Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Kuhn SO; Department of Anesthesiology and Intensive Care Medicine, University Hospital Greifswald, Greifswald, Germany., Jarczak D; Department of Intensive Care Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Motsch J; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany., Hempel G; Department of Anesthesiology and Intensive Care Medicine, University of Leipzig Medical Centre, Leipzig, Germany., Weiler N; Department of Anesthesiology and Intensive Care Medicine, University Medical Center Kiel, Kiel, Germany., Weyland A; Research Center Neurosensory Science, Carl von Ossietzky Universität Oldenburg, Oldenburg, Germany., Drüner M; Department of Anesthesiology and Intensive Care Medicine, Hospital Emden, Emden, Germany., Gründling M; Department of Anesthesiology and Intensive Care Medicine, University Hospital Greifswald, Greifswald, Germany., Meybohm P; Department of Anesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Würzburg, Germany., Richter D; Department of Anesthesiology, University Hospital Heidelberg, Heidelberg, Germany., Jaschinski U; Department of Anesthesiology and Surgical Intensive Care Medicine, University Hospital Augsburg, Augsburg, Germany., Moerer O; Department of Anesthesiology, University Medical Center, Georg-August-University, Göttingen, Germany., Günther U; University Clinic of Anaesthesiology, Intensive Care, Emergency Medicine and Pain Therapy, Klinikum Oldenburg, Oldenburg, Germany., Schädler D; Department of Anesthesiology and Intensive Care Medicine, University Medical Center Kiel, Kiel, Germany., Weiss R; Department of Anesthesiology, Surgical Intensive Care Medicine and Pain Therapy, University Hospital Münster, Munster, Germany., Putensen C; Division of Intensive Care Medicine, Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany., Castellanos I; Department of Anesthesiology, University Hospital, Erlangen, Germany., Kurzai O; Institute for Hygiene and Microbiology, Julius Maximilians University Würzburg, Würzburg, Germany.; National Reference Center for Invasive Fungal Infections NRZMyk, Leibniz Institute for Natural Product Research and Infection Biology-Hans-Knoell-Insitute, Jena, Germany., Schlattmann P; Institute of Medical Statistics, Computer Sciences and Data Science, Jena University Hospital, Jena, Germany., Cornely OA; Department I of Internal Medicine, Excellence Center for Medical Mycology (ECMM), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Chair Translational Research, Faculty of Medicine and University Hospital Cologne, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, Clinical Trials Centre Cologne (ZKS Köln), University of Cologne, Cologne, Germany.; German Centre for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Bauer M; Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany.; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany., Thomas-Rüddel D; Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany.; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany. |
| Corporate Authors: | SepNet Study Group |
| Source: | Intensive care medicine [Intensive Care Med] 2022 Jul; Vol. 48 (7), pp. 865-875. Date of Electronic Publication: 2022 Jun 16. |
| Publication Type: | Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-1238 |
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| DOI: | 10.1007/s00134-022-06733-x |
