Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia.
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| Title: | Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia. |
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| Authors: | Garcia-Bermudez J; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA., Badgley MA; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA., Prasad S; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA., Baudrier L; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA., Liu Y; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA., La K; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA., Soula M; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA., Williams RT; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA., Yamaguchi N; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA., Hwang RF; Department of Breast Surgical Oncology, Division of Surgery, MD Anderson Cancer Center, University of Texas, Houston, TX, USA., Taylor LJ; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA., de Stanchina E; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rostandy B; The Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Alwaseem H; The Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Molina H; The Proteomics Resource Center, The Rockefeller University, New York, NY, USA., Bar-Sagi D; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, USA. dafna.bar-sagi@nyulangone.org., Birsoy K; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA. kbirsoy@rockefeller.edu. |
| Source: | Nature metabolism [Nat Metab] 2022 Jun; Vol. 4 (6), pp. 724-738. Date of Electronic Publication: 2022 Jun 20. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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