Coordinated activation of TGF-β and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication.

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Title: Coordinated activation of TGF-β and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication.
Authors: Stavropoulos A; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Divolis G; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Manioudaki M; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Gavriil A; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Kloukina I; Center of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Perrea DN; Laboratory of Experimental Surgery and Surgical Research N.S. Christeas, Athens University Medical School, National and Kapodistrian University of Athens, Athens, Greece., Sountoulidis A; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Ford E; Center of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Doulou A; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Apostolidou A; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Katsantoni E; Center of Basic Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Ritvos O; Department of Bacteriology and Immunology and Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Germanidis G; First Department of Internal Medicine, AHEPA Hospital, Aristotle University of Thessaloniki, School of Medicine, Thessaloniki, Greece., Xilouri M; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Sideras P; Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
Source: Science signaling [Sci Signal] 2022 Jun 28; Vol. 15 (740), pp. eabn4395. Date of Electronic Publication: 2022 Jun 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1937-9145
DOI:10.1126/scisignal.abn4395