Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy.

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Title: Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy.
Authors: Hingorani DV; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA., Allevato MM; Department of Pharmacology, University of California San Diego, La Jolla, CA, 92093, USA., Camargo MF; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA., Lesperance J; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA., Quraishi MA; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA., Aguilera J; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA., Franiak-Pietryga I; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA., Scanderbeg DJ; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA., Wang Z; Department of Pharmacology, University of California San Diego, La Jolla, CA, 92093, USA., Molinolo AA; Department of Pathology, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego, Moores Cancer Center, La Jolla, CA, 92093, USA., Alvarado D; Celldex Therapeutics, Hampton, NJ, 08827, USA., Sharabi AB; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego, Moores Cancer Center, La Jolla, CA, 92093, USA., Bui JD; Department of Pathology, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego, Moores Cancer Center, La Jolla, CA, 92093, USA., Cohen EEW; UC San Diego, Moores Cancer Center, La Jolla, CA, 92093, USA.; Department of Medicine, Division of Hematology and Oncology, University of California San Diego, La Jolla, CA, 92093, USA., Adams SR; Department of Pharmacology, University of California San Diego, La Jolla, CA, 92093, USA., Gutkind JS; Department of Pharmacology, University of California San Diego, La Jolla, CA, 92093, USA.; UC San Diego, Moores Cancer Center, La Jolla, CA, 92093, USA., Advani SJ; Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, 92093, USA. sjadvani@ucsd.edu.; UC San Diego, Moores Cancer Center, La Jolla, CA, 92093, USA. sjadvani@ucsd.edu.
Source: Nature communications [Nat Commun] 2022 Jul 05; Vol. 13 (1), pp. 3869. Date of Electronic Publication: 2022 Jul 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-022-31601-z