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Cannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice.

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Title: Cannabinoid CB1 receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice.
Authors: Sánchez-de la Torre A; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain., Aguado T; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain., Huerga-Gómez A; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain., Santamaría S; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain., Gentile A; Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.; University Medical Center, Institute of Physiological Chemistry, Mainz, Germany., Chara JC; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.; Achucarro Basque Center for Neuroscience, Leioa, Spain., Matute C; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.; Achucarro Basque Center for Neuroscience, Leioa, Spain., Monory K; University Medical Center, Institute of Physiological Chemistry, Mainz, Germany., Mato S; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.; Achucarro Basque Center for Neuroscience, Leioa, Spain.; Biocruces, Bizkaia, Spain., Guzmán M; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain., Lutz B; University Medical Center, Institute of Physiological Chemistry, Mainz, Germany., Galve-Roperh I; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain., Palazuelos J; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain. j.palazuelos@ucm.es.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain. j.palazuelos@ucm.es.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain. j.palazuelos@ucm.es.
Source: Cell death & disease [Cell Death Dis] 2022 Jul 07; Vol. 13 (7), pp. 585. Date of Electronic Publication: 2022 Jul 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
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  Data: Cannabinoid CB<subscript>1</subscript> receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice.
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  Data: <searchLink fieldCode="AU" term="%22Sánchez-de+la+Torre+A%22">Sánchez-de la Torre A</searchLink>; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Aguado+T%22">Aguado T</searchLink>; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Huerga-Gómez+A%22">Huerga-Gómez A</searchLink>; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Santamaría+S%22">Santamaría S</searchLink>; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gentile+A%22">Gentile A</searchLink>; Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy.; University Medical Center, Institute of Physiological Chemistry, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Chara+JC%22">Chara JC</searchLink>; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.; Achucarro Basque Center for Neuroscience, Leioa, Spain.<br /><searchLink fieldCode="AU" term="%22Matute+C%22">Matute C</searchLink>; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.; Achucarro Basque Center for Neuroscience, Leioa, Spain.<br /><searchLink fieldCode="AU" term="%22Monory+K%22">Monory K</searchLink>; University Medical Center, Institute of Physiological Chemistry, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Mato+S%22">Mato S</searchLink>; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Neurosciences, University of the Basque Country UPV/EHU, Leioa, Spain.; Achucarro Basque Center for Neuroscience, Leioa, Spain.; Biocruces, Bizkaia, Spain.<br /><searchLink fieldCode="AU" term="%22Guzmán+M%22">Guzmán M</searchLink>; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Lutz+B%22">Lutz B</searchLink>; University Medical Center, Institute of Physiological Chemistry, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Galve-Roperh+I%22">Galve-Roperh I</searchLink>; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Palazuelos+J%22">Palazuelos J</searchLink>; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain. j.palazuelos@ucm.es.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain. j.palazuelos@ucm.es.; Department of Biochemistry and Molecular Biology, Complutense University, Instituto Universitario de Investigación en Neuroquímica (IUIN), Madrid, Spain. j.palazuelos@ucm.es.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2022 Jul 07; Vol. 13 (7), pp. 585. <i>Date of Electronic Publication: </i>2022 Jul 07.
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