Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in rats.
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| Title: | Development of a multi-route physiologically based pharmacokinetic (PBPK) model for nanomaterials: a comparison between a traditional versus a new route-specific approach using gold nanoparticles in rats. |
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| Authors: | Chou WC; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, 1225 Center Drive, Gainesville, FL, 32610, USA.; Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL, 32608, USA.; Institute of Computational Comparative Medicine, Kansas State University, Manhattan, KS, 66506, USA., Cheng YH; Institute of Computational Comparative Medicine, Kansas State University, Manhattan, KS, 66506, USA.; Nanotechnology Innovation Center of Kansas State, Kansas State University, Manhattan, KS, 66506, USA., Riviere JE; Institute of Computational Comparative Medicine, Kansas State University, Manhattan, KS, 66506, USA.; Nanotechnology Innovation Center of Kansas State, Kansas State University, Manhattan, KS, 66506, USA.; 1Data Consortium, Kansas State University, Olathe, KS, 66061, USA., Monteiro-Riviere NA; Nanotechnology Innovation Center of Kansas State, Kansas State University, Manhattan, KS, 66506, USA., Kreyling WG; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Epidemiology, Ingolstaedter Landstrasse 1, Neuherberg, 85764, Munich, Germany., Lin Z; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, 1225 Center Drive, Gainesville, FL, 32610, USA. linzhoumeng@ufl.edu.; Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL, 32608, USA. linzhoumeng@ufl.edu.; Institute of Computational Comparative Medicine, Kansas State University, Manhattan, KS, 66506, USA. linzhoumeng@ufl.edu.; Nanotechnology Innovation Center of Kansas State, Kansas State University, Manhattan, KS, 66506, USA. linzhoumeng@ufl.edu. |
| Source: | Particle and fibre toxicology [Part Fibre Toxicol] 2022 Jul 08; Vol. 19 (1), pp. 47. Date of Electronic Publication: 2022 Jul 08. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101236354 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-8977 (Electronic) Linking ISSN: 17438977 NLM ISO Abbreviation: Part Fibre Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1743-8977 |
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| DOI: | 10.1186/s12989-022-00489-4 |