CaMKII binds both substrates and activators at the active site.

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Title: CaMKII binds both substrates and activators at the active site.
Authors: Özden C; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA; Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA 01003, USA., Sloutsky R; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA., Mitsugi T; Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan., Santos N; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA., Agnello E; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA., Gaubitz C; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Foster J; Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA 01003, USA., Lapinskas E; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA., Esposito EA; Malvern Panalytical, Northampton, MA 01060, USA., Saneyoshi T; Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan., Kelch BA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Garman SC; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA., Hayashi Y; Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan., Stratton MM; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA. Electronic address: mstratton@umass.edu.
Source: Cell reports [Cell Rep] 2022 Jul 12; Vol. 40 (2), pp. 111064.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2022.111064