LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease.
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| Title: | LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease. |
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| Authors: | Kedariti M; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Frattini E; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Dino Ferrari Center, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Baden P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany., Cogo S; Department of Biology, University of Padova, Padova, Italy.; School of Biological Sciences, University of Reading, Reading, UK., Civiero L; Department of Biology, University of Padova, Padova, Italy.; IRCCS San Camillo Hospital, Venice, Italy.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padova, Italy., Ziviani E; Department of Biology, University of Padova, Padova, Italy., Zilio G; Department of Biology, University of Padova, Padova, Italy., Bertoli F; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany., Aureli M; Department of of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Kaganovich A; Department of Biology, University of Padova, Padova, Italy.; Laboratory of Neurogenetics, NIA, Bethesda, USA., Cookson MR; Laboratory of Neurogenetics, NIA, Bethesda, USA., Stefanis L; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.; Department of Neurology, University of Athens Medical School, Athens, Greece., Surface M; Department of Neurology, Columbia University Irving Medical Center, New York, USA., Deleidi M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany., Di Fonzo A; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Dino Ferrari Center, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Alcalay RN; Department of Neurology, Columbia University Irving Medical Center, New York, USA., Rideout H; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece. hrideout08@gmail.com., Greggio E; Department of Biology, University of Padova, Padova, Italy. elisa.greggio@unipd.it.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padova, Italy. elisa.greggio@unipd.it., Plotegher N; Department of Biology, University of Padova, Padova, Italy. nicoletta.plotegher@unipd.it. |
| Source: | NPJ Parkinson's disease [NPJ Parkinsons Dis] 2022 Jul 19; Vol. 8 (1), pp. 92. Date of Electronic Publication: 2022 Jul 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2373-8057 |
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| DOI: | 10.1038/s41531-022-00354-3 |
