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LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease.

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Title: LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease.
Authors: Kedariti M; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece., Frattini E; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Dino Ferrari Center, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Baden P; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany., Cogo S; Department of Biology, University of Padova, Padova, Italy.; School of Biological Sciences, University of Reading, Reading, UK., Civiero L; Department of Biology, University of Padova, Padova, Italy.; IRCCS San Camillo Hospital, Venice, Italy.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padova, Italy., Ziviani E; Department of Biology, University of Padova, Padova, Italy., Zilio G; Department of Biology, University of Padova, Padova, Italy., Bertoli F; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany., Aureli M; Department of of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy., Kaganovich A; Department of Biology, University of Padova, Padova, Italy.; Laboratory of Neurogenetics, NIA, Bethesda, USA., Cookson MR; Laboratory of Neurogenetics, NIA, Bethesda, USA., Stefanis L; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.; Department of Neurology, University of Athens Medical School, Athens, Greece., Surface M; Department of Neurology, Columbia University Irving Medical Center, New York, USA., Deleidi M; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany., Di Fonzo A; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Dino Ferrari Center, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Alcalay RN; Department of Neurology, Columbia University Irving Medical Center, New York, USA., Rideout H; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece. hrideout08@gmail.com., Greggio E; Department of Biology, University of Padova, Padova, Italy. elisa.greggio@unipd.it.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padova, Italy. elisa.greggio@unipd.it., Plotegher N; Department of Biology, University of Padova, Padova, Italy. nicoletta.plotegher@unipd.it.
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2022 Jul 19; Vol. 8 (1), pp. 92. Date of Electronic Publication: 2022 Jul 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson's disease.
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  Data: <searchLink fieldCode="AU" term="%22Kedariti+M%22">Kedariti M</searchLink>; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Frattini+E%22">Frattini E</searchLink>; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Dino Ferrari Center, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Baden+P%22">Baden P</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany.<br /><searchLink fieldCode="AU" term="%22Cogo+S%22">Cogo S</searchLink>; Department of Biology, University of Padova, Padova, Italy.; School of Biological Sciences, University of Reading, Reading, UK.<br /><searchLink fieldCode="AU" term="%22Civiero+L%22">Civiero L</searchLink>; Department of Biology, University of Padova, Padova, Italy.; IRCCS San Camillo Hospital, Venice, Italy.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Ziviani+E%22">Ziviani E</searchLink>; Department of Biology, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Zilio+G%22">Zilio G</searchLink>; Department of Biology, University of Padova, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Bertoli+F%22">Bertoli F</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany.<br /><searchLink fieldCode="AU" term="%22Aureli+M%22">Aureli M</searchLink>; Department of of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Kaganovich+A%22">Kaganovich A</searchLink>; Department of Biology, University of Padova, Padova, Italy.; Laboratory of Neurogenetics, NIA, Bethesda, USA.<br /><searchLink fieldCode="AU" term="%22Cookson+MR%22">Cookson MR</searchLink>; Laboratory of Neurogenetics, NIA, Bethesda, USA.<br /><searchLink fieldCode="AU" term="%22Stefanis+L%22">Stefanis L</searchLink>; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.; Department of Neurology, University of Athens Medical School, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Surface+M%22">Surface M</searchLink>; Department of Neurology, Columbia University Irving Medical Center, New York, USA.<br /><searchLink fieldCode="AU" term="%22Deleidi+M%22">Deleidi M</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Tübingen, 72076, Germany.<br /><searchLink fieldCode="AU" term="%22Di+Fonzo+A%22">Di Fonzo A</searchLink>; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Dino Ferrari Center, Neuroscience Section, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Alcalay+RN%22">Alcalay RN</searchLink>; Department of Neurology, Columbia University Irving Medical Center, New York, USA.<br /><searchLink fieldCode="AU" term="%22Rideout+H%22">Rideout H</searchLink>; Division of Basic Neurosciences, Biomedical Research Foundation of the Academy of Athens, Athens, Greece. hrideout08@gmail.com.<br /><searchLink fieldCode="AU" term="%22Greggio+E%22">Greggio E</searchLink>; Department of Biology, University of Padova, Padova, Italy. elisa.greggio@unipd.it.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padova, Italy. elisa.greggio@unipd.it.<br /><searchLink fieldCode="AU" term="%22Plotegher+N%22">Plotegher N</searchLink>; Department of Biology, University of Padova, Padova, Italy. nicoletta.plotegher@unipd.it.
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  Data: <searchLink fieldCode="JN" term="%22101675390%22">NPJ Parkinson's disease</searchLink> [NPJ Parkinsons Dis] 2022 Jul 19; Vol. 8 (1), pp. 92. <i>Date of Electronic Publication: </i>2022 Jul 19.
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