An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.

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Title: An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD.
Authors: Bauer CS; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Cohen RN; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Sironi F; Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156, Milan, Italy., Livesey MR; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Gillingwater TH; Edinburgh Medical School: Biomedical Sciences, University of Edinburgh, Hugh Robson Building, Edinburgh, EH8 9XD, UK.; Euan MacDonald Centre for Motor Neuron Disease Research, Chancellor's Building, University of Edinburgh, Edinburgh, EH16 4SB, UK., Highley JR; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Fillingham DJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Coldicott I; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Smith EF; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Gibson YB; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Webster CP; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Grierson AJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK., Bendotti C; Laboratory of Molecular Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156, Milan, Italy., De Vos KJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK. k.de_vos@sheffield.ac.uk.; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK. k.de_vos@sheffield.ac.uk.
Source: Acta neuropathologica [Acta Neuropathol] 2022 Sep; Vol. 144 (3), pp. 437-464. Date of Electronic Publication: 2022 Jul 25.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0533
DOI:10.1007/s00401-022-02470-z