A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment.
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| Title: | A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment. |
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| Authors: | Kuo CL; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan., Chou HY; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan., Lien HW; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan., Yeh CA; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan., Wang JR; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan., Chen CH; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan., Fan CC; Department of research and development, Marker Exploration Corporation, Taipei, Taiwan., Hsu CP; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan., Kao TY; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan., Ko TM; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan., Lee AY; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan. alanylee@nhri.edu.tw.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 40402, Taiwan. alanylee@nhri.edu.tw.; Department of Life Sciences, College of Life Science, National Central University, Taoyuan, 32031, Taiwan. alanylee@nhri.edu.tw.; Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan. alanylee@nhri.edu.tw. |
| Source: | Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2023 Feb; Vol. 72 (2), pp. 351-369. Date of Electronic Publication: 2022 Jul 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-0851 |
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| DOI: | 10.1007/s00262-022-03255-9 |
