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A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment.

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Title: A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment.
Authors: Kuo CL; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan., Chou HY; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan., Lien HW; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan., Yeh CA; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan., Wang JR; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan., Chen CH; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan., Fan CC; Department of research and development, Marker Exploration Corporation, Taipei, Taiwan., Hsu CP; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan., Kao TY; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan., Ko TM; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan., Lee AY; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan. alanylee@nhri.edu.tw.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 40402, Taiwan. alanylee@nhri.edu.tw.; Department of Life Sciences, College of Life Science, National Central University, Taoyuan, 32031, Taiwan. alanylee@nhri.edu.tw.; Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan. alanylee@nhri.edu.tw.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2023 Feb; Vol. 72 (2), pp. 351-369. Date of Electronic Publication: 2022 Jul 27.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Fc-VEGF chimeric fusion enhances PD-L1 immunotherapy via inducing immune reprogramming and infiltration in the immunosuppressive tumor microenvironment.
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  Data: <searchLink fieldCode="AU" term="%22Kuo+CL%22">Kuo CL</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chou+HY%22">Chou HY</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lien+HW%22">Lien HW</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+CA%22">Yeh CA</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+JR%22">Wang JR</searchLink>; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CH%22">Chen CH</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fan+CC%22">Fan CC</searchLink>; Department of research and development, Marker Exploration Corporation, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CP%22">Hsu CP</searchLink>; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kao+TY%22">Kao TY</searchLink>; Department of Medical Laboratory Science and Biotechnology, Yuanpei University of Medical Technology, Hsinchu, 300, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ko+TM%22">Ko TM</searchLink>; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, 300, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei, 11529, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+AY%22">Lee AY</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Zhunan, Miaoli, 35053, Taiwan. alanylee@nhri.edu.tw.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 40402, Taiwan. alanylee@nhri.edu.tw.; Department of Life Sciences, College of Life Science, National Central University, Taoyuan, 32031, Taiwan. alanylee@nhri.edu.tw.; Department of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan. alanylee@nhri.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%228605732%22">Cancer immunology, immunotherapy : CII</searchLink> [Cancer Immunol Immunother] 2023 Feb; Vol. 72 (2), pp. 351-369. <i>Date of Electronic Publication: </i>2022 Jul 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8605732 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0851 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203407004%22">03407004 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Immunother <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00262-022-03255-9
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        Text: English
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              Text: 2023 Feb
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              Y: 2023
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