Protein Scaffold-Based Multimerization of Soluble ACE2 Efficiently Blocks SARS-CoV-2 Infection In Vitro and In Vivo.
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| Title: | Protein Scaffold-Based Multimerization of Soluble ACE2 Efficiently Blocks SARS-CoV-2 Infection In Vitro and In Vivo. |
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| Authors: | Kayabolen A; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey., Akcan U; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey., Özturan D; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey., Ulbegi-Polat H; Genetic Engineering and Biotechnology Institute, TUBITAK Marmara Research Center, Kocaeli, 41470, Turkey., Sahin GN; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey., Pinarbasi-Degirmenci N; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey., Bayraktar C; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey., Soyler G; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey., Sarayloo E; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey.; Department of Biotechnology, Beykoz Institute of Life Sciences and Biotechnology (BILSAB), Bezmialem Vakif University, Istanbul, 34820, Turkey., Nurtop E; Koç University Isbank Center for Infectious Diseases (KUISCID), Istanbul, 34010, Turkey., Ozer B; Koç University Isbank Center for Infectious Diseases (KUISCID), Istanbul, 34010, Turkey., Guney-Esken G; Koç University Isbank Center for Infectious Diseases (KUISCID), Istanbul, 34010, Turkey., Barlas T; Koç University Isbank Center for Infectious Diseases (KUISCID), Istanbul, 34010, Turkey., Yildirim IS; Genetic Engineering and Biotechnology Institute, TUBITAK Marmara Research Center, Kocaeli, 41470, Turkey., Dogan O; Koç University Isbank Center for Infectious Diseases (KUISCID), Istanbul, 34010, Turkey.; Koç University School of Medicine, Department of Medical Microbiology, Istanbul, 34010, Turkey., Karahuseyinoglu S; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey.; Koç University School of Medicine, Department of Histology and Embryology, Istanbul, 34450, Türkiye., Lack NA; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey.; Vancouver Prostate Centre, University of British Columbia, Vancouver, BC V6H 3Z6, Canada., Kaya M; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey., Albayrak C; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey.; Department of Biotechnology, Beykoz Institute of Life Sciences and Biotechnology (BILSAB), Bezmialem Vakif University, Istanbul, 34820, Turkey., Can F; Koç University Isbank Center for Infectious Diseases (KUISCID), Istanbul, 34010, Turkey.; Koç University School of Medicine, Department of Medical Microbiology, Istanbul, 34010, Turkey., Solaroglu I; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey.; Department of Basic Sciences, Loma Linda University, Loma Linda, CA, 92354, USA., Bagci-Onder T; Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul, 34450, Turkey. |
| Source: | Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2022 Sep; Vol. 9 (27), pp. e2201294. Date of Electronic Publication: 2022 Jul 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2198-3844 |
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| DOI: | 10.1002/advs.202201294 |
