Functional and biological heterogeneity of KRASQ61 mutations.
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| Title: | Functional and biological heterogeneity of KRASQ61 mutations. |
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| Authors: | Huynh MV; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Hobbs GA; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC 29425, USA., Schaefer A; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Pierobon M; Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA 20110, USA., Carey LM; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Diehl JN; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., DeLiberty JM; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Thurman RD; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Cooke AR; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Goodwin CM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Cook JH; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA., Lin L; Department of Molecular and Integrative Physiology, University of Michigan Health System, Ann Arbor, MI 48109, USA., Waters AM; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Rashid NU; Department of Biostatistics, University of North Carolina at Chapel Hill, NC 27955, USA., Petricoin EF 3rd; Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA 20110, USA., Campbell SL; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Haigis KM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA.; Harvard Digestive Disease Center, Harvard Medical School, Boston, MA 02115, USA., Simeone DM; Perlmutter Cancer Center, New York University, New York, NY 10016, USA., Lyssiotis CA; Department of Molecular and Integrative Physiology, University of Michigan Health System, Ann Arbor, MI 48109, USA.; Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48198, USA.; University of Michigan Comprehensive Cancer Center, Ann Arbor, MI 48109, USA., Cox AD; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Department of Radiation Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Der CJ; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. |
| Source: | Science signaling [Sci Signal] 2022 Aug 09; Vol. 15 (746), pp. eabn2694. Date of Electronic Publication: 2022 Aug 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1937-9145 |
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| DOI: | 10.1126/scisignal.abn2694 |
