Lack of direct bone effect of tofacitinib, a JAK inhibitor, in juvenile rats and evaluation of the association between offspring growth and femur length.

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Title: Lack of direct bone effect of tofacitinib, a JAK inhibitor, in juvenile rats and evaluation of the association between offspring growth and femur length.
Authors: Campion SN; Pfizer Worldwide Research, Development & Medical, Groton, CT 06340, USA. Electronic address: sarah.campion@pfizer.com., Potter DM; Pfizer Worldwide Research, Development & Medical, Cambridge, MA 02139, USA., Bowman CJ; Pfizer Worldwide Research, Development & Medical, Groton, CT 06340, USA., Catlin NR; Pfizer Worldwide Research, Development & Medical, Groton, CT 06340, USA., Davis S; Charles River Laboratories, Ashland, OH 44805, USA., Millard C; Charles River Laboratories, Ashland, OH 44805, USA., Nowland WS; Pfizer Worldwide Research, Development & Medical, Groton, CT 06340, USA., Stethem CM; Pfizer Worldwide Research, Development & Medical, Groton, CT 06340, USA., Hollingshead BD; Pfizer Worldwide Research, Development & Medical, Cambridge, MA 02139, USA., Radi ZA; Pfizer Worldwide Research, Development & Medical, Cambridge, MA 02139, USA., Coder PS; Charles River Laboratories, Ashland, OH 44805, USA., Cappon GD; Pfizer Worldwide Research, Development & Medical, Groton, CT 06340, USA.
Source: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2022 Oct; Vol. 113, pp. 35-41. Date of Electronic Publication: 2022 Aug 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Pergamon In Cooperation With The Reproductive Toxicology Center Country of Publication: United States NLM ID: 8803591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1708 (Electronic) Linking ISSN: 08906238 NLM ISO Abbreviation: Reprod Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-1708
DOI:10.1016/j.reprotox.2022.08.002