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Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids.

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Title: Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids.
Authors: Song H; Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, 94143, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94143, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA., Bucher S; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA., Rosenberg K; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA.; Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, 94143, USA., Tsui M; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA.; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA., Burhan D; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA., Hoffman D; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA.; Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, 94143, USA., Cho SJ; Department of Pathology, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA., Rangaswami A; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA.; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA., Breese M; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA., Leung S; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA., Ventura MVP; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA., Sweet-Cordero EA; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA.; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA., Huang FW; Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA. franklin.huang@ucsf.edu.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, 94143, USA. franklin.huang@ucsf.edu.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94143, USA. franklin.huang@ucsf.edu.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA. franklin.huang@ucsf.edu.; Department of Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, CA, 94121, USA. franklin.huang@ucsf.edu.; Chan Zuckerberg Biohub, San Francisco, CA, 94158, USA. franklin.huang@ucsf.edu., Nijagal A; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA. Amar.Nijagal@ucsf.edu.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA. Amar.Nijagal@ucsf.edu.; Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, 94143, USA. Amar.Nijagal@ucsf.edu.; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA. Amar.Nijagal@ucsf.edu.; Eli and Edythe Broad Center of Regeneration Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA. Amar.Nijagal@ucsf.edu., Wang B; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA. bruce.wang@ucsf.edu.; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA. bruce.wang@ucsf.edu.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA. bruce.wang@ucsf.edu.; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA. bruce.wang@ucsf.edu.
Source: Nature communications [Nat Commun] 2022 Aug 25; Vol. 13 (1), pp. 4878. Date of Electronic Publication: 2022 Aug 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids.
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  Data: <searchLink fieldCode="AU" term="%22Song+H%22">Song H</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, 94143, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94143, USA.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Bucher+S%22">Bucher S</searchLink>; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Rosenberg+K%22">Rosenberg K</searchLink>; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA.; Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Tsui+M%22">Tsui M</searchLink>; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA.; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Burhan+D%22">Burhan D</searchLink>; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Hoffman+D%22">Hoffman D</searchLink>; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA.; Division of Pediatric Surgery, Department of Surgery, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Cho+SJ%22">Cho SJ</searchLink>; Department of Pathology, University of California, San Francisco, San Francisco, CA, 94143, USA.; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Rangaswami+A%22">Rangaswami A</searchLink>; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA.; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Breese+M%22">Breese M</searchLink>; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Leung+S%22">Leung S</searchLink>; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Ventura+MVP%22">Ventura MVP</searchLink>; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Sweet-Cordero+EA%22">Sweet-Cordero EA</searchLink>; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA.; Division of Oncology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, 94143, USA.<br /><searchLink fieldCode="AU" term="%22Huang+FW%22">Huang FW</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA. franklin.huang@ucsf.edu.; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, 94143, USA. franklin.huang@ucsf.edu.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, 94143, USA. franklin.huang@ucsf.edu.; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA. franklin.huang@ucsf.edu.; Department of Medicine, San Francisco Veterans Affairs Medical Center, San Francisco, CA, 94121, USA. franklin.huang@ucsf.edu.; Chan Zuckerberg Biohub, San Francisco, CA, 94158, USA. franklin.huang@ucsf.edu.<br /><searchLink fieldCode="AU" term="%22Nijagal+A%22">Nijagal A</searchLink>; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA. 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Amar.Nijagal@ucsf.edu.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, 94143, USA. bruce.wang@ucsf.edu.; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA, 94143, USA. bruce.wang@ucsf.edu.; The Liver Center, University of California, San Francisco, San Francisco, CA, 94143, USA. bruce.wang@ucsf.edu.; The Pediatric Liver Center at UCSF Benioff Childrens' Hospitals, San Francisco, CA, 94143, USA. bruce.wang@ucsf.edu.
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