Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study.

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Title: Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study.
Authors: Vandriel SM; Division of Gastroenterology, Hepatology and Nutrition , The Hospital for Sick Children and the University of Toronto , Toronto , Canada., Li LT; The Center for Pediatric Liver Diseases , Children's Hospital of Fudan University , Shanghai , China., She H; The Center for Pediatric Liver Diseases , Children's Hospital of Fudan University , Shanghai , China., Wang JS; The Center for Pediatric Liver Diseases , Children's Hospital of Fudan University , Shanghai , China., Gilbert MA; Division of Genomic Diagnostics , Department of Pathology and Laboratory Medicine , The Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine , Philadelphia , Pennsylvania , USA., Jankowska I; Department of Gastroenterology, Hepatology, Nutrition Disturbances and Pediatrics , The Children's Memorial Health Institute , Warsaw , Poland., Czubkowski P; Department of Gastroenterology, Hepatology, Nutrition Disturbances and Pediatrics , The Children's Memorial Health Institute , Warsaw , Poland., Gliwicz-Miedzińska D; Department of Gastroenterology, Hepatology, Nutrition Disturbances and Pediatrics , The Children's Memorial Health Institute , Warsaw , Poland., Gonzales EM; Pediatric Hepatology and Liver Transplantation Unit , National Reference Centre for Rare Pediatric Liver Diseases (Biliary Atresia and Genetic Cholestasis) , FILFOIE, ERN RARE LIVER, Bicêtre Hospital, AP-HP and Inserm U1193, Hepatinov, Université Paris-Saclay , Le Kremlin-Bicêtre , France., Jacquemin E; Pediatric Hepatology and Liver Transplantation Unit , National Reference Centre for Rare Pediatric Liver Diseases (Biliary Atresia and Genetic Cholestasis) , FILFOIE, ERN RARE LIVER, Bicêtre Hospital, AP-HP and Inserm U1193, Hepatinov, Université Paris-Saclay , Le Kremlin-Bicêtre , France., Bouligand J; Service de Génétique Moléculaire, Pharmacogénétique et Hormonologie, Hôpitaux Universitaires Paris-Saclay , Assistance Publique-Hôpitaux de Paris , Centre Hospitalier Universitaire de Bicêtre , Le Kremlin-Bicêtre , France., Spinner NB; Division of Genomic Diagnostics , Department of Pathology and Laboratory Medicine , The Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine , Philadelphia , Pennsylvania , USA., Loomes KM; Division of Gastroenterology, Hepatology and Nutrition , The Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine , Philadelphia , Pennsylvania , USA., Piccoli DA; Division of Gastroenterology, Hepatology and Nutrition , The Children's Hospital of Philadelphia and the University of Pennsylvania Perelman School of Medicine , Philadelphia , Pennsylvania , USA., D'Antiga L; Pediatric Hepatology, Gastroenterology and Transplantation , Ospedale Papa Giovanni XXIII , Bergamo , Italy., Nicastro E; Pediatric Hepatology, Gastroenterology and Transplantation , Ospedale Papa Giovanni XXIII , Bergamo , Italy., Sokal É; Service De Gastroentérologie & Hépatologie Pédiatrique , Cliniques Universitaires Saint-Luc , Brussels , Belgium., Demaret T; Service De Gastroentérologie & Hépatologie Pédiatrique , Cliniques Universitaires Saint-Luc , Brussels , Belgium., Ebel NH; Division of Gastroenterology , Department of Pediatrics , Stanford University School of Medicine , Palo Alto , California , USA., Feinstein JA; Department of Pediatrics (Cardiology) , Stanford University School of Medicine , Lucile Packard Children's Hospital , Palo Alto , California , USA., Fawaz R; Department of Pediatrics , Yale University School of Medicine , New Haven , Connecticut , USA., Nastasio S; Division of Gastroenterology, Hepatology, & Nutrition , Boston Children's Hospital and Harvard Medical School , Boston , Massachusetts , USA., Lacaille F; Department of Pediatric Gastroenterology, and Nutrition , Necker-Enfants Malades Hospital , University of Paris , Paris , France., Debray D; Pediatric Liver Unit , National Reference Centre for Rare Pediatric Liver Diseases (Biliary Atresia and Genetic Cholestasis) , FILFOIE, ERN RARE LIVER, Necker-Enfants Malades Hospital , University of Paris , Paris , France., Arnell H; Department of Paediatric Gastroenterology, Hepatology and Nutrition , Astrid Lindgren Children's Hospital, Karolinska University Hospital , Stockholm , Sweden.; Department of Women's and Children's Health , Karolinska Institutet , Stockholm , Sweden., Fischler B; Department of Paediatric Gastroenterology, Hepatology and Nutrition , Astrid Lindgren Children's Hospital, Karolinska University Hospital , Stockholm , Sweden.; CLINTEC , Karolinska Institutet , Stockholm , Sweden., Siew S; Department of Gastroenterology , The Children's Hospital at Westmead , Sydney , Australia., Stormon M; Department of Gastroenterology , The Children's Hospital at Westmead , Sydney , Australia., Karpen SJ; Division of Pediatric Gastroenterology, Hepatology & Nutrition , Children's Healthcare of Atlanta & Emory University School of Medicine , Atlanta , Georgia , USA., Romero R; Division of Pediatric Gastroenterology, Hepatology & Nutrition , Children's Healthcare of Atlanta & Emory University School of Medicine , Atlanta , Georgia , USA., Kim KM; Department of Pediatrics , University of Ulsan College of Medicine , Asan Medical Center Children's Hospital , Seoul , Republic of Korea., Baek WY; Department of Pediatrics , University of Ulsan College of Medicine , Asan Medical Center Children's Hospital , Seoul , Republic of Korea., Hardikar W; Department of Gastroenterology and Clinical Nutrition , Royal Children's Hospital , Melbourne , Australia., Shankar S; Mazumdar Shaw Medical Center , Narayana Health , Bangalore , India., Roberts AJ; Department of Paediatric Gastroenterology , Starship Child Health , Auckland , New Zealand., Evans HM; Department of Paediatric Gastroenterology , Starship Child Health , Auckland , New Zealand., Jensen MK; Division of Pediatric Gastroenterology, Hepatology and Nutrition , University of Utah , Salt Lake City , Utah , USA., Kavan M; Division of Pediatric Gastroenterology, Hepatology and Nutrition , University of Utah , Salt Lake City , Utah , USA., Sundaram SS; Section of Gastroenterology, Hepatology and Nutrition , Department of Pediatrics and the Digestive Health Institute , Children's Hospital of Colorado and University of Colorado School of Medicine , Aurora , Colorado , USA., Chaidez A; Section of Gastroenterology, Hepatology and Nutrition , Department of Pediatrics and the Digestive Health Institute , Children's Hospital of Colorado and University of Colorado School of Medicine , Aurora , Colorado , USA., Karthikeyan P; Leeds Teaching Hospitals NHS Trust , Leeds Children's Hospital , Leeds , UK., Sanchez MC; Pediatric Gastroenterology and Hepatology Division , Hospital Italiano Buenos Aires , Buenos Aires , Argentina., Cavalieri ML; Pediatric Gastroenterology and Hepatology Division , Hospital Italiano Buenos Aires , Buenos Aires , Argentina., Verkade HJ; Department of Pediatrics , Center for Liver, Digestive, and Metabolic Diseases , University Medical Center Groningen , Groningen , The Netherlands., Lee WS; Faculty of Medicine, Department of Paediatrics , University of Malaya , Kuala Lumpur , Malaysia., Squires JE; Division of Pediatric Gastroenterology and Hepatology , Department of Pediatrics , University of Pittsburgh School of Medicine , Pittsburgh , Pennsylvania , USA., Hajinicolaou C; Division of Paediatric Gastroenterology , Department of Paediatrics and Child Health , Chris Hani Baragwanath Academic Hospital , University of the Witwatersrand , Johannesburg , South Africa., Lertudomphonwanit C; Division of Gastroenterology , Department of Pediatrics , Ramathibodi Hospital Mahidol University , Bangkok , Thailand., Fischer RT; Department of Gastroenterology, Section of Hepatology , Children's Mercy Kansas City , Kansas City , Missouri , USA., Larson-Nath C; Division of Pediatric Gastroenterology, Hepatology, and Nutrition , University of Minnesota , Minneapolis , Minnesota , USA., Mozer-Glassberg Y; Institute of Gastroenterology, Nutrition and Liver Diseases , Schneider Children's Medical Center of Israel , Petah Tikva , Israel., Arikan C; Department of Pediatric Gastroenterology and Organ Transplant , Koc University School of Medicine , Istanbul , Turkey., Lin HC; Division of Pediatric Gastroenterology , Department of Pediatrics , Oregon Health and Science University , Portland , Oregon , USA., Bernabeu JQ; Pediatric Hepatology and Liver Transplant Department , Hospital Universitari Vall d'Hebron , Barcelona , Spain., Alam S; Department of Pediatric Hepatology , Institute of Liver and Biliary Sciences , New Delhi , India., Kelly DA; Liver Unit , Birmingham Women's & Children's Hospital NHS Trust, University of Birmingham , Birmingham , UK., Carvalho E; Pediatric Gastroenterology Department , Hospital da Criança de Brasília , Centro Universitário de Brasília , Brasília , Brazil., Ferreira CT; Pediatric Gastroenterology Service , Hospital da Criança Santo Antôni, Universidade Federal de Ciências da Saúde de Porto Alegre , Complexo Hospitalar Santa Casa , Porto Alegre , RS , Brazil., Indolfi G; Paediatric and Liver Unit , Department Neurofarba , University of Florence and Meyer Children's University Hospital , Florence , Italy., Quiros-Tejeira RE; Department of Pediatrics , Children's Hospital & Medical Center and University of Nebraska Medical Center , Omaha , Nebraska , USA., Bulut P; Division of Pediatric Gastroenterology and Hepatology , Phoenix Children's Hospital , Phoenix , USA., Calvo PL; Pediatric Gastroenterology Unit , Regina Margherita Children's Hospital , Azienda Ospedaliera-Universitaria Citta' della Salute e della Scienza , Turin , Italy., Önal Z; Pediatric Gastroenterology, Hepatology and Nutrition Department, Istanbul Medical Faculty , Istanbul University , Istanbul , Turkey., Valentino PL; Department of Pediatrics , Yale University School of Medicine , New Haven , Connecticut , USA., Desai DM; Solid Organ Transplant Department , Children's Health - Children's Medical Center , Dallas , Texas , USA., Eshun J; Department of Pediatric Gastroenterology , Le Bonheur Children's Hospital, The University of Tennessee Health Science Center , Memphis , Texas , USA., Rogalidou M; Division of Gastroenterology & Hepatology, First Department of Pediatrics , 'Agia Sofia' Children's Hospital , University of Athens , Athens , Greece., Dezsőfi A; First Department of Paediatrics , Semmelweis University , Budapest , Hungary., Wiecek S; Department of Pediatrics , Medical University of Silesia in Katowice , Katowice , Poland., Nebbia G; Servizio di Epatologia Pediatrica , Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico , Milan , Italy., Pinto RB; Division of Pediatric Gastroenterology of Hospital da Criança Conceição do Grupo Hospitalar Conceição , Porto Alegre , RS , Brazil., Wolters VM; Department of Pediatric Gastroenterology , University Medical Center Utrecht , Utrecht , The Netherlands., Tamara ML; Paediatric Gastroenterology Unit , Cruces University Hospital , Bilbao , Spain., Zizzo AN; Division of Paediatric Gastroenterology and Hepatology , London Health Sciences Centre, Children's Hospital , Western University , London , Ontario , Canada., Garcia J; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Miami Transplant Institute , University of Miami , Miami , Florida , USA., Schwarz K; Division of Pediatric Gastroenterology , University of California San Diego, Rady Children's Hospital San Diego , San Diego , California , USA., Beretta M; Faculty of Health Sciences, Wits Donald Gordon Medical Centre , University of the Witwatersrand , Johannesburg , South Africa., Sandahl TD; Department of Hepatology and Gastroenterology , Aarhus University Hospital , Aarhus , Denmark., Jimenez-Rivera C; Division of Gastroenterology, Hepatology and Nutrition , Children's Hospital of Eastern Ontario , Ottawa , Canada., Kerkar N; Division of Pediatric Gastroenterology, Hepatology and Nutrition , Department of Pediatrics , University of Rochester Medical Center , Rochester , New York , USA., Brecelj J; Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics , Faculty of Medicine , University Medical Center Ljubljana , Ljubljana , Slovenia., Mujawar Q; Section of Pediatric Gastroenterology , Department of Pediatrics , University of Manitoba , Winnipeg , Canada., Rock N; Department of Paediatrics, Gynaecology and Obstetrics , Geneva University Hospitals, University of Geneva , Geneva , Switzerland., Busoms CM; Pediatric Gastroenterology Hepatology and Nutrition Unit , Hospital Sant Joan de Déu , Esplugues de Llobregat , Spain., Karnsakul W; Department of Pediatrics , Johns Hopkins University School of Medicine , Baltimore , Maryland , USA., Lurz E; Department of Pediatrics , Dr. von Hauner Children's Hospital , University Hospital , LMU Munich , Munich , Germany., Santos-Silva E; Pediatric Gastroenterology Unit , Centro Hospitalar Universitário Do Porto , Porto , Portugal., Blondet N; Gastroenterology and Hepatology , Seattle Children's Hospital , Seattle , Washington , USA., Bujanda L; Department of Hepatology and Gastroenterology , Biodonostia Health Research Institute, Donostia University Hospital , Universidad del País Vasco (UPV/EHU) , Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) , San Sebastián , Spain., Shah U; Harvard Medical School , Massachusetts General Hospital for Children , Boston , Massachusetts , USA., Thompson RJ; Institute of Liver Studies , King's College London , London , UK., Hansen BE; Toronto General Hospital University Health Network , Toronto , Ontario , Canada.; Institute of Health Policy, Management and Evaluation , Toronto , Ontario , Canada., Kamath BM; Division of Gastroenterology, Hepatology and Nutrition , The Hospital for Sick Children and the University of Toronto , Toronto , Canada.
Corporate Authors: Global ALagille Alliance (GALA) Study Group
Source: Hepatology (Baltimore, Md.) [Hepatology] 2023 Feb 01; Vol. 77 (2), pp. 512-529. Date of Electronic Publication: 2022 Oct 13.
Publication Type: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1527-3350
DOI:10.1002/hep.32761