Safety of First-Line Nivolumab Plus Ipilimumab in Patients With Metastatic NSCLC: A Pooled Analysis of CheckMate 227, CheckMate 568, and CheckMate 817.

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Title: Safety of First-Line Nivolumab Plus Ipilimumab in Patients With Metastatic NSCLC: A Pooled Analysis of CheckMate 227, CheckMate 568, and CheckMate 817.
Authors: Paz-Ares LG; Medical Oncology Department, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain. Electronic address: lpazaresr@seom.org., Ciuleanu TE; Department of Medical Oncology, Institutul Oncologic Prof. Dr. Ion Chiricuta and University of Medicine and Pharmacy Iulia Hatieganu, Cluj-Napoca, Romania., Pluzanski A; Department of Lung Cancer and Chest Tumours, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland., Lee JS; Department of Hematology/Oncology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea., Gainor JF; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts., Otterson GA; The Ohio State University-James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio., Audigier-Valette C; Orientation Oncologique, Hôpital Sainte-Musse, Toulon, France., Ready N; Department of Medicine, Duke University School of Medicine, Durham, North Carolina., Schenker M; Department of Medical Oncology, Sf Nectarie Oncology Center, Craiova, Romania., Linardou H; Fourth Oncology Department and Comprehensive Clinical Trials Center, Metropolitan Hospital, Athens, Greece., Caro RB; Medical Oncology Department, Hospital Universitario Virgen Del Rocio, Instituto de Biomedicina de Seville, Seville, Spain., Provencio M; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain., Zurawski B; Chemotherapy Department, Ambulatorium Chemioterapii, Bydgoszcz, Poland., Lee KH; Medical Oncology, Chungbuk National University Hospital, Cheongju-si, Republic of Korea., Kim SW; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Caserta C; Medical Oncology Department, Santa Maria Hospital, Terni, Italy., Ramalingam SS; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia., Spigel DR; Thoracic Medical Oncology, Sarah Cannon Research Institute/Tennessee Oncology PLLC, Nashville, Tennessee., Brahmer JR; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland., Reck M; Department of Thoracic Oncology, Airway Research Center North, German Center for Lung Research, LungClinic, Grosshansdorf, Germany., O'Byrne KJ; Princess Alexandra Hospital, Translational Research Institute and Queensland University of Technology, Brisbane, Queensland, Australia., Girard N; Institut du Thorax Curie-Montsouris, Institut Curie, Paris, France., Popat S; Lung Unit, Royal Marsden Hospital, London, United Kingdom; The Institute of Cancer Research, University of London, London, United Kingdom., Peters S; Oncology Department, Lausanne University Hospital, Lausanne, Switzerland., Memaj A; Global Biometrics and Data Sciences, Bristol Myers Squibb, Princeton, New Jersey., Nathan F; Medical Oncology Department, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain; Medical Oncology Department, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain., Aanur N; OneClinical, Bristol Myers Squibb, Princeton, New Jersey., Borghaei H; Hematology and Oncology Department, Fox Chase Cancer Center, Temple Health System, Philadelphia, Pennsylvania.
Source: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2023 Jan; Vol. 18 (1), pp. 79-92. Date of Electronic Publication: 2022 Aug 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101274235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-1380 (Electronic) Linking ISSN: 15560864 NLM ISO Abbreviation: J Thorac Oncol Subsets: MEDLINE
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  Data: Safety of First-Line Nivolumab Plus Ipilimumab in Patients With Metastatic NSCLC: A Pooled Analysis of CheckMate 227, CheckMate 568, and CheckMate 817.
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  Data: <searchLink fieldCode="AU" term="%22Paz-Ares+LG%22">Paz-Ares LG</searchLink>; Medical Oncology Department, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain. Electronic address: lpazaresr@seom.org.<br /><searchLink fieldCode="AU" term="%22Ciuleanu+TE%22">Ciuleanu TE</searchLink>; Department of Medical Oncology, Institutul Oncologic Prof. Dr. Ion Chiricuta and University of Medicine and Pharmacy Iulia Hatieganu, Cluj-Napoca, Romania.<br /><searchLink fieldCode="AU" term="%22Pluzanski+A%22">Pluzanski A</searchLink>; Department of Lung Cancer and Chest Tumours, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Lee+JS%22">Lee JS</searchLink>; Department of Hematology/Oncology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Gainor+JF%22">Gainor JF</searchLink>; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Otterson+GA%22">Otterson GA</searchLink>; The Ohio State University-James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio.<br /><searchLink fieldCode="AU" term="%22Audigier-Valette+C%22">Audigier-Valette C</searchLink>; Orientation Oncologique, Hôpital Sainte-Musse, Toulon, France.<br /><searchLink fieldCode="AU" term="%22Ready+N%22">Ready N</searchLink>; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.<br /><searchLink fieldCode="AU" term="%22Schenker+M%22">Schenker M</searchLink>; Department of Medical Oncology, Sf Nectarie Oncology Center, Craiova, Romania.<br /><searchLink fieldCode="AU" term="%22Linardou+H%22">Linardou H</searchLink>; Fourth Oncology Department and Comprehensive Clinical Trials Center, Metropolitan Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Caro+RB%22">Caro RB</searchLink>; Medical Oncology Department, Hospital Universitario Virgen Del Rocio, Instituto de Biomedicina de Seville, Seville, Spain.<br /><searchLink fieldCode="AU" term="%22Provencio+M%22">Provencio M</searchLink>; Medical Oncology Department, Hospital Universitario Puerta de Hierro, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Zurawski+B%22">Zurawski B</searchLink>; Chemotherapy Department, Ambulatorium Chemioterapii, Bydgoszcz, Poland.<br /><searchLink fieldCode="AU" term="%22Lee+KH%22">Lee KH</searchLink>; Medical Oncology, Chungbuk National University Hospital, Cheongju-si, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SW%22">Kim SW</searchLink>; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Caserta+C%22">Caserta C</searchLink>; Medical Oncology Department, Santa Maria Hospital, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Ramalingam+SS%22">Ramalingam SS</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.<br /><searchLink fieldCode="AU" term="%22Spigel+DR%22">Spigel DR</searchLink>; Thoracic Medical Oncology, Sarah Cannon Research Institute/Tennessee Oncology PLLC, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Brahmer+JR%22">Brahmer JR</searchLink>; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins Kimmel Cancer Center, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Reck+M%22">Reck M</searchLink>; Department of Thoracic Oncology, Airway Research Center North, German Center for Lung Research, LungClinic, Grosshansdorf, Germany.<br /><searchLink fieldCode="AU" term="%22O'Byrne+KJ%22">O'Byrne KJ</searchLink>; Princess Alexandra Hospital, Translational Research Institute and Queensland University of Technology, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Girard+N%22">Girard N</searchLink>; Institut du Thorax Curie-Montsouris, Institut Curie, Paris, France.<br /><searchLink fieldCode="AU" term="%22Popat+S%22">Popat S</searchLink>; Lung Unit, Royal Marsden Hospital, London, United Kingdom; The Institute of Cancer Research, University of London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Peters+S%22">Peters S</searchLink>; Oncology Department, Lausanne University Hospital, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Memaj+A%22">Memaj A</searchLink>; Global Biometrics and Data Sciences, Bristol Myers Squibb, Princeton, New Jersey.<br /><searchLink fieldCode="AU" term="%22Nathan+F%22">Nathan F</searchLink>; Medical Oncology Department, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain; Medical Oncology Department, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Aanur+N%22">Aanur N</searchLink>; OneClinical, Bristol Myers Squibb, Princeton, New Jersey.<br /><searchLink fieldCode="AU" term="%22Borghaei+H%22">Borghaei H</searchLink>; Hematology and Oncology Department, Fox Chase Cancer Center, Temple Health System, Philadelphia, Pennsylvania.
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