View in EDS

Evaluation of an ester-linked immunosuppressive payload: A case study in understanding the stability and cleavability of ester-containing ADC linkers.

Saved in:
Bibliographic Details
Title: Evaluation of an ester-linked immunosuppressive payload: A case study in understanding the stability and cleavability of ester-containing ADC linkers.
Authors: Jackson CP; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Fang S; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Benjamin SR; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Alayi T; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Hathout Y; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Gillen SM; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Handel JP; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Brems BM; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Howe JM; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States., Tumey LN; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States. Electronic address: NTumey@binghamton.edu.
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Nov 01; Vol. 75, pp. 128953. Date of Electronic Publication: 2022 Sep 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 36058468
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Evaluation of an ester-linked immunosuppressive payload: A case study in understanding the stability and cleavability of ester-containing ADC linkers.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Jackson+CP%22">Jackson CP</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Fang+S%22">Fang S</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Benjamin+SR%22">Benjamin SR</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Alayi+T%22">Alayi T</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Hathout+Y%22">Hathout Y</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Gillen+SM%22">Gillen SM</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Handel+JP%22">Handel JP</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Brems+BM%22">Brems BM</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Howe+JM%22">Howe JM</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States.<br /><searchLink fieldCode="AU" term="%22Tumey+LN%22">Tumey LN</searchLink>; School of Pharmacy and Pharmaceutical Sciences, Binghamton University, P.O. Box 6000, Binghamton, NY 13902, United States. Electronic address: NTumey@binghamton.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2022 Nov 01; Vol. 75, pp. 128953. <i>Date of Electronic Publication: </i>2022 Sep 01.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107377 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3405 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220960894X%22">0960894X </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem Lett <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36058468
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.bmcl.2022.128953
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 128953
    Titles:
      – TitleFull: Evaluation of an ester-linked immunosuppressive payload: A case study in understanding the stability and cleavability of ester-containing ADC linkers.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Jackson CP
      – PersonEntity:
          Name:
            NameFull: Fang S
      – PersonEntity:
          Name:
            NameFull: Benjamin SR
      – PersonEntity:
          Name:
            NameFull: Alayi T
      – PersonEntity:
          Name:
            NameFull: Hathout Y
      – PersonEntity:
          Name:
            NameFull: Gillen SM
      – PersonEntity:
          Name:
            NameFull: Handel JP
      – PersonEntity:
          Name:
            NameFull: Brems BM
      – PersonEntity:
          Name:
            NameFull: Howe JM
      – PersonEntity:
          Name:
            NameFull: Tumey LN
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 11
              Text: 2022 Nov 01
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 1464-3405
          Numbering:
            – Type: volume
              Value: 75
          Titles:
            – TitleFull: Bioorganic & medicinal chemistry letters
              Type: main
ResultId 1