A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters.
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| Title: | A single-administration therapeutic interfering particle reduces SARS-CoV-2 viral shedding and pathogenesis in hamsters. |
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| Authors: | Chaturvedi S; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Beutler N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037., Vasen G; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Pablo M; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Chen X; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Calia G; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158., Buie L; VxBiosciences Inc., Berkeley, CA 94707., Rodick R; VxBiosciences Inc., Berkeley, CA 94707., Smith D; Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, CA 92121., Rogers T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.; Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, CA 92121., Weinberger LS; Gladstone|UCSF Center for Cell Circuitry, San Francisco, CA 94158.; Gladstone Institute of Virology, Gladstone Institutes, San Francisco, CA 94158.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158.; Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158. |
| Source: | Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Sep 27; Vol. 119 (39), pp. e2204624119. Date of Electronic Publication: 2022 Sep 08. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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