Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway.

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Title: Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway.
Authors: Maynard S; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Hall A; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Galanos P; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Rizza S; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Yamamoto T; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Gram HH; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Munk SHN; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Shoaib M; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, DK-2200 Copenhagen, Denmark., Sørensen CS; Biotech Research and Innovation Centre (BRIC), University of Copenhagen, DK-2200 Copenhagen, Denmark., Bohr VA; Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK-2200 Copenhagen, Denmark.; Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA., Lerdrup M; The DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, DK-2200 Copenhagen, Denmark., Maya-Mendoza A; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark., Bartek J; Danish Cancer Society Research Center, DK-2100 Copenhagen, Denmark.; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institute, SE-17177 Stockholm, Sweden.
Source: Nucleic acids research [Nucleic Acids Res] 2022 Sep 23; Vol. 50 (17), pp. 9948-9965.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1362-4962
DOI:10.1093/nar/gkac741