A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling.

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Title: A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling.
Authors: Mondal C; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Gacha-Garay MJ; Biochemistry and Cell Biology Department, Stony Brook University, Stony Brook, NY 11794, USA., Larkin KA; Biochemistry and Cell Biology Department, Stony Brook University, Stony Brook, NY 11794, USA., Adikes RC; Biochemistry and Cell Biology Department, Stony Brook University, Stony Brook, NY 11794, USA., Di Martino JS; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Chien CC; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Fraser M; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Eni-Aganga I; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Agullo-Pascual E; Microscopy and Advanced Bioimaging Core, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Cialowicz K; Microscopy and Advanced Bioimaging Core, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Ozbek U; Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Naba A; Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL 60612, USA; University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, IL 60612, USA., Gaitas A; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Fu TM; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA., Upadhyayula S; Department of Molecular and Cellular Biology, UC Berkeley, CA 94720, USA., Betzig E; Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA 20147, USA; Department of Molecular and Cellular Biology, UC Berkeley, CA 94720, USA., Matus DQ; Biochemistry and Cell Biology Department, Stony Brook University, Stony Brook, NY 11794, USA., Martin BL; Biochemistry and Cell Biology Department, Stony Brook University, Stony Brook, NY 11794, USA., Bravo-Cordero JJ; Department of Medicine, Division of Hematology and Oncology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: josejavier.bravo-cordero@mssm.edu.
Source: Cell reports [Cell Rep] 2022 Sep 20; Vol. 40 (12), pp. 111358.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2211-1247
DOI:10.1016/j.celrep.2022.111358