Dihydromyricetin alleviates methotrexate-induced hepatotoxicity via suppressing the TLR4/NF-κB pathway and NLRP3 inflammasome/caspase 1 axis.
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| Title: | Dihydromyricetin alleviates methotrexate-induced hepatotoxicity via suppressing the TLR4/NF-κB pathway and NLRP3 inflammasome/caspase 1 axis. |
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| Authors: | Matouk AI; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia University, El-Minia, Egypt. Electronic address: Asmaa.ahmed@mu.edu.eg., Awad EM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia University, El-Minia, Egypt. Electronic address: eman_moftah90@yahoo.com., El-Tahawy NFG; Department of Histology and Cell Biology, Faculty of Medicine, Minia University, El-Minia, Egypt. Electronic address: nashogo@yahoo.com., El-Sheikh AAK; Basic Health Sciences Department, College of Medicine, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia. Electronic address: azza.elsheikh@mu.edu.eg., Waz S; Department of Biochemistry, Faculty of Pharmacy, Minia University, El-Minia, Egypt. Electronic address: shaimaaminia@mu.edu.eg. |
| Source: | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Nov; Vol. 155, pp. 113752. Date of Electronic Publication: 2022 Sep 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1950-6007 |
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| DOI: | 10.1016/j.biopha.2022.113752 |