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A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.

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Title: A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
Authors: Han Y; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Tan L; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; Center for Energy Metabolism and Reproduction, Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Zhou T; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; Stem Cell Research Facility, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Yang L; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Carrau L; Department of Microbiology, New York University, 430 E 29th Street, New York, NY 10016, USA., Lacko LA; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Saeed M; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA; National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, Boston, MA 02118, USA., Zhu J; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Zhao Z; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Nilsson-Payant BE; Department of Microbiology, New York University, 430 E 29th Street, New York, NY 10016, USA., Lira Neto FT; Department of Urology, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil., Cahir C; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; The Tri-Institutional PhD Program in Chemical Biology, New York, NY, USA., Giani AM; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Chai JC; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA., Li Y; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA., Dong X; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Moroziewicz D; The New York Stem Cell Foundation Research Institute, 619 West 54th Street, 3rd Floor, New York, NY 10019, USA., Paull D; The New York Stem Cell Foundation Research Institute, 619 West 54th Street, 3rd Floor, New York, NY 10019, USA., Zhang T; Genomic Resource Core Facility, Weill Cornell Medical College, New York, NY 10065, USA., Koo S; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; Weill Cornell Neuroscience PhD Program, New York, NY, USA., Tan C; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Danziger R; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Ba Q; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Feng L; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, China., Chen Z; Department of Population Health Sciences, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Zhong A; Stem Cell Research Facility, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA., Wise GJ; Department of Urology, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., Xiang JZ; Genomic Resource Core Facility, Weill Cornell Medical College, New York, NY 10065, USA., Wang H; School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China., Schwartz RE; Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA., tenOever BR; Department of Microbiology, New York University, 430 E 29th Street, New York, NY 10016, USA., Noggle SA; The New York Stem Cell Foundation Research Institute, 619 West 54th Street, 3rd Floor, New York, NY 10019, USA., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA., Qi Q; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA., Evans T; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA., Chen S; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA. Electronic address: shc2034@med.cornell.edu.
Corporate Authors: NYSCF Global Stem Cell Array Team; The New York Stem Cell Foundation Research Institute, 619 West 54th Street, 3rd Floor, New York, NY 10019, USA.
Source: Cell stem cell [Cell Stem Cell] 2022 Oct 06; Vol. 29 (10), pp. 1475-1490.e6.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants.
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  Data: <searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Tan+L%22">Tan L</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; Center for Energy Metabolism and Reproduction, Institute of Biomedicine and Biotechnology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Zhou+T%22">Zhou T</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; Stem Cell Research Facility, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Carrau+L%22">Carrau L</searchLink>; Department of Microbiology, New York University, 430 E 29th Street, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Lacko+LA%22">Lacko LA</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Saeed+M%22">Saeed M</searchLink>; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA; National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Nilsson-Payant+BE%22">Nilsson-Payant BE</searchLink>; Department of Microbiology, New York University, 430 E 29th Street, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Lira+Neto+FT%22">Lira Neto FT</searchLink>; Department of Urology, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil.<br /><searchLink fieldCode="AU" term="%22Cahir+C%22">Cahir C</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; The Tri-Institutional PhD Program in Chemical Biology, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Giani+AM%22">Giani AM</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Chai+JC%22">Chai JC</searchLink>; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.<br /><searchLink fieldCode="AU" term="%22Dong+X%22">Dong X</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Moroziewicz+D%22">Moroziewicz D</searchLink>; The New York Stem Cell Foundation Research Institute, 619 West 54th Street, 3rd Floor, New York, NY 10019, USA.<br /><searchLink fieldCode="AU" term="%22Paull+D%22">Paull D</searchLink>; The New York Stem Cell Foundation Research Institute, 619 West 54th Street, 3rd Floor, New York, NY 10019, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+T%22">Zhang T</searchLink>; Genomic Resource Core Facility, Weill Cornell Medical College, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Koo+S%22">Koo S</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; Weill Cornell Neuroscience PhD Program, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tan+C%22">Tan C</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Danziger+R%22">Danziger R</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Ba+Q%22">Ba Q</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Feng+L%22">Feng L</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA; Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Population Health Sciences, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Zhong+A%22">Zhong A</searchLink>; Stem Cell Research Facility, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Wise+GJ%22">Wise GJ</searchLink>; Department of Urology, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Xiang+JZ%22">Xiang JZ</searchLink>; Genomic Resource Core Facility, Weill Cornell Medical College, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Schwartz+RE%22">Schwartz RE</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA; Department of Physiology, Biophysics, and Systems Biology, Weill Cornell Medicine, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22tenOever+BR%22">tenOever BR</searchLink>; Department of Microbiology, New York University, 430 E 29th Street, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Noggle+SA%22">Noggle SA</searchLink>; The New York Stem Cell Foundation Research Institute, 619 West 54th Street, 3rd Floor, New York, NY 10019, USA.<br /><searchLink fieldCode="AU" term="%22Rice+CM%22">Rice CM</searchLink>; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Qi+Q%22">Qi Q</searchLink>; Department of Epidemiology & Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.<br /><searchLink fieldCode="AU" term="%22Evans+T%22">Evans T</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Department of Surgery, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA. Electronic address: shc2034@med.cornell.edu.
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