Immunotherapy with CD25/CD71-allodepleted T cells to improve T-cell reconstitution after matched unrelated donor hematopoietic stem cell transplant: a randomized trial.

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Title: Immunotherapy with CD25/CD71-allodepleted T cells to improve T-cell reconstitution after matched unrelated donor hematopoietic stem cell transplant: a randomized trial.
Authors: Peggs KS; Department of Hematology, University College London Hospital, London, UK., Albon SJ; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK., Oporto Espuelas M; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK. Electronic address: m.oporto@ucl.ac.uk., Irving C; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK., Richardson R; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK., Casanovas-Company J; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK., Wallace R; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK; Molecular Hematology Section, University College London Great Ormond Street Institute of Child Health, London, UK., Guvenel A; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK., Ghorashian S; Molecular Hematology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Department of Hematology, Great Ormond Street Hospital for Children, London, UK., Collura A; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK., Subramaniyam M; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK., Flutter B; Gene and Cell Therapy, Great Ormond Street Hospital for Children, London, UK; Molecular Hematology Section, University College London Great Ormond Street Institute of Child Health, London, UK., Popova B; Cancer Research UK and University College London Cancer Trials Center, London, UK., Castro F; Cancer Research UK and University College London Cancer Trials Center, London, UK., Lopes A; Cancer Research UK and University College London Cancer Trials Center, London, UK., Champion K; Cancer Research UK and University College London Cancer Trials Center, London, UK., Schofield O; Cancer Research UK and University College London Cancer Trials Center, London, UK., Clifton-Hadley L; Cancer Research UK and University College London Cancer Trials Center, London, UK., Taylor T; Department of Hematology, University College London Hospital, London, UK., Farrell M; Department of Hematology, Manchester Royal Infirmary, Manchester, UK., Adams S; Department of Hematology, Great Ormond Street Hospital for Children, London, UK., Gilmour KC; Cell Therapy and Immunology, Camelia Botnar Laboratories, Great Ormond Street Hospital for Children, London, UK., Mackinnon S; Department of Hematology, University College London Hospital, London, UK., Tholouli E; Department of Hematology, Manchester Royal Infirmary, Manchester, UK., Amrolia PJ; Molecular and Cellular Immunology Section, University College London Great Ormond Street Institute of Child Health, London, UK; Department of Bone Marrow Transplantation, Great Ormond Street Hospital for Children, London, UK. Electronic address: persis.amrolia@gosh.nhs.uk.
Source: Cytotherapy [Cytotherapy] 2023 Jan; Vol. 25 (1), pp. 82-93. Date of Electronic Publication: 2022 Oct 09.
Publication Type: Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 100895309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2566 (Electronic) Linking ISSN: 14653249 NLM ISO Abbreviation: Cytotherapy Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1477-2566
DOI:10.1016/j.jcyt.2022.08.010