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Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine.

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Title: Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine.
Authors: O'Connell CL; Jane Anne Nohl Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., Baer MR; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland., Ørskov AD; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Danish Stem Cell Center (Danstem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Saini SK; Department of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark., Duong VH; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland., Kropf P; Fox Chase Cancer Center, Philadelphia, Pennsylvania., Hansen JW; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Danish Stem Cell Center (Danstem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tsao-Wei D; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., Jang HS; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan., Emadi A; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland., Holmberg-Thyden S; Department of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark., Cowland J; Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark., Brinker BT; Medical Oncology, Cancer and Hematology Centers of West Michigan, Grand Rapids, Michigan., Horwood K; Jane Anne Nohl Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California., Burgos R; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan., Hostetter G; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan., Youngblood BA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee., Hadrup SR; Department of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark., Issa JP; Coriell Institute for Medical Research, Camden, New Jersey., Jones P; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan., Baylin SB; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland., Siddiqi I; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California., Grønbaek K; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Danish Stem Cell Center (Danstem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Dec 15; Vol. 28 (24), pp. 5306-5316.
Publication Type: Clinical Trial, Phase I; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine.
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  Data: <searchLink fieldCode="AU" term="%22O'Connell+CL%22">O'Connell CL</searchLink>; Jane Anne Nohl Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Baer+MR%22">Baer MR</searchLink>; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Ørskov+AD%22">Ørskov AD</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Danish Stem Cell Center (Danstem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Saini+SK%22">Saini SK</searchLink>; Department of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Duong+VH%22">Duong VH</searchLink>; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Kropf+P%22">Kropf P</searchLink>; Fox Chase Cancer Center, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Hansen+JW%22">Hansen JW</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Danish Stem Cell Center (Danstem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Tsao-Wei+D%22">Tsao-Wei D</searchLink>; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Jang+HS%22">Jang HS</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan.<br /><searchLink fieldCode="AU" term="%22Emadi+A%22">Emadi A</searchLink>; Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.; University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Holmberg-Thyden+S%22">Holmberg-Thyden S</searchLink>; Department of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Cowland+J%22">Cowland J</searchLink>; Department of Clinical Genetics, Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Brinker+BT%22">Brinker BT</searchLink>; Medical Oncology, Cancer and Hematology Centers of West Michigan, Grand Rapids, Michigan.<br /><searchLink fieldCode="AU" term="%22Horwood+K%22">Horwood K</searchLink>; Jane Anne Nohl Division of Hematology, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Burgos+R%22">Burgos R</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan.<br /><searchLink fieldCode="AU" term="%22Hostetter+G%22">Hostetter G</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan.<br /><searchLink fieldCode="AU" term="%22Youngblood+BA%22">Youngblood BA</searchLink>; Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee.<br /><searchLink fieldCode="AU" term="%22Hadrup+SR%22">Hadrup SR</searchLink>; Department of Health Technology, Section of Experimental and Translational Immunology, Technical University of Denmark, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Issa+JP%22">Issa JP</searchLink>; Coriell Institute for Medical Research, Camden, New Jersey.<br /><searchLink fieldCode="AU" term="%22Jones+P%22">Jones P</searchLink>; Department of Epigenetics, Van Andel Institute, Grand Rapids, Michigan.<br /><searchLink fieldCode="AU" term="%22Baylin+SB%22">Baylin SB</searchLink>; Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Siddiqi+I%22">Siddiqi I</searchLink>; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Grønbaek+K%22">Grønbaek K</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen, Denmark.; Biotech Research and Innovation Centre, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Danish Stem Cell Center (Danstem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2022 Dec 15; Vol. 28 (24), pp. 5306-5316.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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