Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors.

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Title: Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors.
Authors: Huang W; Genentech Inc, South San Francisco, CA, United States., Stader F; Certara UK Limited, Sheffield, United Kingdom., Chan P; Genentech Inc, South San Francisco, CA, United States., Shemesh CS; Genentech Inc, South San Francisco, CA, United States., Chen Y; Genentech Inc, South San Francisco, CA, United States., Gill KL; Certara UK Limited, Sheffield, United Kingdom., Jones HM; Certara UK Limited, Sheffield, United Kingdom., Li L; Certara UK Limited, Sheffield, United Kingdom., Rossato G; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Wu B; Genentech Inc, South San Francisco, CA, United States., Jin JY; Genentech Inc, South San Francisco, CA, United States., Chanu P; Genentech Inc, South San Francisco, CA, United States.
Source: Frontiers in pharmacology [Front Pharmacol] 2022 Sep 26; Vol. 13, pp. 974423. Date of Electronic Publication: 2022 Sep 26 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of a pediatric physiologically-based pharmacokinetic model to support recommended dosing of atezolizumab in children with solid tumors.
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  Data: <searchLink fieldCode="AU" term="%22Huang+W%22">Huang W</searchLink>; Genentech Inc, South San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Stader+F%22">Stader F</searchLink>; Certara UK Limited, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chan+P%22">Chan P</searchLink>; Genentech Inc, South San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Shemesh+CS%22">Shemesh CS</searchLink>; Genentech Inc, South San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Genentech Inc, South San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Gill+KL%22">Gill KL</searchLink>; Certara UK Limited, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jones+HM%22">Jones HM</searchLink>; Certara UK Limited, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Certara UK Limited, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rossato+G%22">Rossato G</searchLink>; F. Hoffmann-La Roche Ltd, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wu+B%22">Wu B</searchLink>; Genentech Inc, South San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Jin+JY%22">Jin JY</searchLink>; Genentech Inc, South San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Chanu+P%22">Chanu P</searchLink>; Genentech Inc, South San Francisco, CA, United States.
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        Value: 10.3389/fphar.2022.974423
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              Text: 2022 Sep 26
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