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Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function.

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Title: Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function.
Authors: Hawley KM; Department of Pediatrics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL 60637., Eclov RJ; Department of Pediatrics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL 60637., Schnorenberg MR; Department of Pediatrics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL 60637.; Medical Scientist Training Program, The University of Chicago, Chicago, IL 60637.; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637., Tian Y; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637., Shah RN; Department of Pediatrics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL 60637., Thomas-Toth AT; Department of Pediatrics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL 60637., Fefferman M; Department of Pediatrics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL 60637., Bird GH; Department of Pediatric Oncology, Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215., Walensky LD; Department of Pediatric Oncology, Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, MA 02215., Tirrell MV; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL 60637.; Argonne National Laboratory, Lemont, IL 60439., LaBelle JL; Department of Pediatrics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL 60637.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Oct 18; Vol. 119 (42), pp. e2209044119. Date of Electronic Publication: 2022 Oct 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2209044119