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IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells.

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Title: IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells.
Authors: Kehl N; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Kilian M; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Michel J; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Wagner TR; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; GMP and Cell Therapy Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Uhrig S; Molecular Precision Oncology Program, National Center for Tumor Diseases, Heidelberg, Germany., Brobeil A; Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany., Sester LS; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany., Blobner S; Department of Translational Oncology, National Center of Tumor Diseases (NCT) and German Cancer Consortium (DKTK), Heidelberg, Germany., Steiger S; Division of Chromatin Networks, BioQuant Center and German Cancer Research Center (DKFZ), Heidelberg, Germany., Hundemer M; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany., Weinhold N; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany., Rippe K; Division of Chromatin Networks, BioQuant Center and German Cancer Research Center (DKFZ), Heidelberg, Germany., Fröhling S; Department of Translational Oncology, National Center of Tumor Diseases (NCT) and German Cancer Consortium (DKTK), Heidelberg, Germany., Eichmüller SB; GMP and Cell Therapy Group, German Cancer Research Center (DKFZ), Heidelberg, Germany., Bunse L; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Müller-Tidow C; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany., Goldschmidt H; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; National Center of Tumor Diseases (NCT) and German Cancer Consortium (DKTK), Heidelberg, Germany., Platten M; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; National Center of Tumor Diseases (NCT) and German Cancer Consortium (DKTK), Heidelberg, Germany.; DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany., Raab MS; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology / Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Friedrich MJ; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany mirco.friedrich@dkfz.de.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2022 Oct; Vol. 10 (10).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells.
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  Data: <searchLink fieldCode="AU" term="%22Kehl+N%22">Kehl N</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Kilian+M%22">Kilian M</searchLink>; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Michel+J%22">Michel J</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Wagner+TR%22">Wagner TR</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; GMP and Cell Therapy Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Uhrig+S%22">Uhrig S</searchLink>; Molecular Precision Oncology Program, National Center for Tumor Diseases, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Brobeil+A%22">Brobeil A</searchLink>; Department of Pathology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sester+LS%22">Sester LS</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Blobner+S%22">Blobner S</searchLink>; Department of Translational Oncology, National Center of Tumor Diseases (NCT) and German Cancer Consortium (DKTK), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Steiger+S%22">Steiger S</searchLink>; Division of Chromatin Networks, BioQuant Center and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hundemer+M%22">Hundemer M</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Weinhold+N%22">Weinhold N</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Rippe+K%22">Rippe K</searchLink>; Division of Chromatin Networks, BioQuant Center and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Fröhling+S%22">Fröhling S</searchLink>; Department of Translational Oncology, National Center of Tumor Diseases (NCT) and German Cancer Consortium (DKTK), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Eichmüller+SB%22">Eichmüller SB</searchLink>; GMP and Cell Therapy Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Bunse+L%22">Bunse L</searchLink>; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Müller-Tidow+C%22">Müller-Tidow C</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Goldschmidt+H%22">Goldschmidt H</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; National Center of Tumor Diseases (NCT) and German Cancer Consortium (DKTK), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Platten+M%22">Platten M</searchLink>; Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; National Center of Tumor Diseases (NCT) and German Cancer Consortium (DKTK), Heidelberg, Germany.; DKFZ Hector Cancer Institute at the University Medical Center Mannheim, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Raab+MS%22">Raab MS</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany.; Clinical Cooperation Unit Molecular Hematology / Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Friedrich+MJ%22">Friedrich MJ</searchLink>; Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany mirco.friedrich@dkfz.de.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
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        Value: 10.1136/jitc-2022-005815
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              Text: 2022 Oct
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