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Combining mass spectrometry and machine learning to discover bioactive peptides.

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Title: Combining mass spectrometry and machine learning to discover bioactive peptides.
Authors: Madsen CT; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark. ctom@novonordisk.com., Refsgaard JC; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Intomics, Kongens Lyngby, Denmark., Teufel FG; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Kjærulff SK; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Intomics, Kongens Lyngby, Denmark., Wang Z; Novo Nordisk Research Centre China, Beijing, China., Meng G; Novo Nordisk Research Centre China, Beijing, China.; Pulmongene LTD. Rm 502, Building 2, No. 9, Yike Road, Zhongguancun Life Science Park, Changping District, Beijing, China., Jessen C; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Heljo P; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Jiang Q; Novo Nordisk Research Centre China, Beijing, China.; Innovent Biologics, Inc. DongPing Jie 168, Suzhou, China., Zhao X; Novo Nordisk Research Centre China, Beijing, China., Wu B; Novo Nordisk Research Centre China, Beijing, China.; QL Biopharmaceutical, Rm 101, Building 7, 20 Life Science Park Road, Beijing, China., Zhou X; Novo Nordisk Research Centre China, Beijing, China.; Crinetics pharmaceuticals, 10222 Barnes Canyon Rd Building 2, San Diego, CA, 92121, USA., Tang Y; Novo Nordisk Research Centre China, Beijing, China.; Roche R&D Center (China) Ltd, Building 5, 371 Lishizhen Road, 201203, Pudong, Shanghai, China., Jeppesen JF; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Kelstrup CD; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Buckley ST; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Tullin S; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Boehringer Ingelheim GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach, Germany., Nygaard-Jensen J; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Boehringer Ingelheim GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach, Germany., Chen X; Novo Nordisk Research Centre China, Beijing, China., Zhang F; Novo Nordisk Research Centre China, Beijing, China.; Structure Therapeutics. 701 Gateway Blvd., South San Francisco, CA, 94080, USA., Olsen JV; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Han D; Novo Nordisk Research Centre China, Beijing, China., Grønborg M; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., de Lichtenberg U; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; The Novo Nordisk Foundation, Tuborg Havnevej 19, 2900, Hellerup, Denmark.
Source: Nature communications [Nat Commun] 2022 Oct 20; Vol. 13 (1), pp. 6235. Date of Electronic Publication: 2022 Oct 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-022-34031-z