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Combining mass spectrometry and machine learning to discover bioactive peptides.

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Title: Combining mass spectrometry and machine learning to discover bioactive peptides.
Authors: Madsen CT; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark. ctom@novonordisk.com., Refsgaard JC; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Intomics, Kongens Lyngby, Denmark., Teufel FG; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Kjærulff SK; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Intomics, Kongens Lyngby, Denmark., Wang Z; Novo Nordisk Research Centre China, Beijing, China., Meng G; Novo Nordisk Research Centre China, Beijing, China.; Pulmongene LTD. Rm 502, Building 2, No. 9, Yike Road, Zhongguancun Life Science Park, Changping District, Beijing, China., Jessen C; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Heljo P; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Jiang Q; Novo Nordisk Research Centre China, Beijing, China.; Innovent Biologics, Inc. DongPing Jie 168, Suzhou, China., Zhao X; Novo Nordisk Research Centre China, Beijing, China., Wu B; Novo Nordisk Research Centre China, Beijing, China.; QL Biopharmaceutical, Rm 101, Building 7, 20 Life Science Park Road, Beijing, China., Zhou X; Novo Nordisk Research Centre China, Beijing, China.; Crinetics pharmaceuticals, 10222 Barnes Canyon Rd Building 2, San Diego, CA, 92121, USA., Tang Y; Novo Nordisk Research Centre China, Beijing, China.; Roche R&D Center (China) Ltd, Building 5, 371 Lishizhen Road, 201203, Pudong, Shanghai, China., Jeppesen JF; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Kelstrup CD; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Buckley ST; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., Tullin S; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Boehringer Ingelheim GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach, Germany., Nygaard-Jensen J; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Boehringer Ingelheim GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach, Germany., Chen X; Novo Nordisk Research Centre China, Beijing, China., Zhang F; Novo Nordisk Research Centre China, Beijing, China.; Structure Therapeutics. 701 Gateway Blvd., South San Francisco, CA, 94080, USA., Olsen JV; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark., Han D; Novo Nordisk Research Centre China, Beijing, China., Grønborg M; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark., de Lichtenberg U; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; The Novo Nordisk Foundation, Tuborg Havnevej 19, 2900, Hellerup, Denmark.
Source: Nature communications [Nat Commun] 2022 Oct 20; Vol. 13 (1), pp. 6235. Date of Electronic Publication: 2022 Oct 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Combining mass spectrometry and machine learning to discover bioactive peptides.
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  Data: <searchLink fieldCode="AU" term="%22Madsen+CT%22">Madsen CT</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark. ctom@novonordisk.com.<br /><searchLink fieldCode="AU" term="%22Refsgaard+JC%22">Refsgaard JC</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Intomics, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Teufel+FG%22">Teufel FG</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.<br /><searchLink fieldCode="AU" term="%22Kjærulff+SK%22">Kjærulff SK</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Intomics, Kongens Lyngby, Denmark.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Novo Nordisk Research Centre China, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Meng+G%22">Meng G</searchLink>; Novo Nordisk Research Centre China, Beijing, China.; Pulmongene LTD. Rm 502, Building 2, No. 9, Yike Road, Zhongguancun Life Science Park, Changping District, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Jessen+C%22">Jessen C</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.<br /><searchLink fieldCode="AU" term="%22Heljo+P%22">Heljo P</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.<br /><searchLink fieldCode="AU" term="%22Jiang+Q%22">Jiang Q</searchLink>; Novo Nordisk Research Centre China, Beijing, China.; Innovent Biologics, Inc. DongPing Jie 168, Suzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Novo Nordisk Research Centre China, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wu+B%22">Wu B</searchLink>; Novo Nordisk Research Centre China, Beijing, China.; QL Biopharmaceutical, Rm 101, Building 7, 20 Life Science Park Road, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhou+X%22">Zhou X</searchLink>; Novo Nordisk Research Centre China, Beijing, China.; Crinetics pharmaceuticals, 10222 Barnes Canyon Rd Building 2, San Diego, CA, 92121, USA.<br /><searchLink fieldCode="AU" term="%22Tang+Y%22">Tang Y</searchLink>; Novo Nordisk Research Centre China, Beijing, China.; Roche R&D Center (China) Ltd, Building 5, 371 Lishizhen Road, 201203, Pudong, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Jeppesen+JF%22">Jeppesen JF</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.<br /><searchLink fieldCode="AU" term="%22Kelstrup+CD%22">Kelstrup CD</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.<br /><searchLink fieldCode="AU" term="%22Buckley+ST%22">Buckley ST</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.<br /><searchLink fieldCode="AU" term="%22Tullin+S%22">Tullin S</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Boehringer Ingelheim GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach, Germany.<br /><searchLink fieldCode="AU" term="%22Nygaard-Jensen+J%22">Nygaard-Jensen J</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; Boehringer Ingelheim GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach, Germany.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Novo Nordisk Research Centre China, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Novo Nordisk Research Centre China, Beijing, China.; Structure Therapeutics. 701 Gateway Blvd., South San Francisco, CA, 94080, USA.<br /><searchLink fieldCode="AU" term="%22Olsen+JV%22">Olsen JV</searchLink>; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Han+D%22">Han D</searchLink>; Novo Nordisk Research Centre China, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Grønborg+M%22">Grønborg M</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.<br /><searchLink fieldCode="AU" term="%22de+Lichtenberg+U%22">de Lichtenberg U</searchLink>; Global Research Technologies, Novo Nordisk A/S, Maaloev, Denmark.; The Novo Nordisk Foundation, Tuborg Havnevej 19, 2900, Hellerup, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2022 Oct 20; Vol. 13 (1), pp. 6235. <i>Date of Electronic Publication: </i>2022 Oct 20.
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