Pharmacokinetics, bioavailability, and plasma protein binding study of glytrexate, a novel multitarget antifolate.
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| Title: | Pharmacokinetics, bioavailability, and plasma protein binding study of glytrexate, a novel multitarget antifolate. |
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| Authors: | Xiang J; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Wu M; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Wang J; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Lin M; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Sun M; Department of General Practice, The Second Hospital, Hebei Medical University, Shijiazhuang, China., Li X; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Xing R; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Guo R; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Gu J; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Lyu T; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Wang L; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China., Shi X; Key Laboratory of Innovative Drug Research and Evaluation in Hebei Province, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China.; Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, Shijiazhuang, China. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2022 Oct 04; Vol. 13, pp. 1001308. Date of Electronic Publication: 2022 Oct 04 (Print Publication: 2022). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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