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Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine.

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Title: Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine.
Authors: Li D; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Martinez DR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Chen H; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Barr M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Lee E; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Parks R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Mielke D; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA., Edwards W; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Newman A; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Bock KW; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20814, USA., Minai M; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20814, USA., Nagata BM; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20814, USA., Gagne M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20814, USA., Douek DC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20814, USA., DeMarco CT; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Denny TN; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Oguin TH 3rd; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Brown A; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Rountree W; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Wang Y; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Mansouri K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA., Edwards RJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Ferrari G; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA., Sempowski GD; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Eaton A; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA., Tang J; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD, 20871, USA., Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA., Santra S; Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA., Pardi N; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, 19104, USA., Weissman D; Department of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Tomai MA; Corporate Research Materials Lab, 3M Company, St Paul, MN, 55144, USA., Fox CB; Infectious Disease Research Institute, Seattle, WA, 98104, USA., Moore IN; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20814, USA., Andersen H; BIOQUAL, Rockville, MD, 20850, USA., Lewis MG; BIOQUAL, Rockville, MD, 20850, USA., Golding H; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD, 20871, USA., Seder R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20814, USA., Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD, 20871, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Montefiori DC; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA., Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. kevin.saunders@duke.edu.; Department of Surgery, Duke University School of Medicine, Durham, NC, 27710, USA. kevin.saunders@duke.edu.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA. kevin.saunders@duke.edu.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, 27710, USA. kevin.saunders@duke.edu., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, 27710, USA. barton.haynes@duke.edu.; Department of Medicine, Duke University School of Medicine, Durham, NC, 27710, USA. barton.haynes@duke.edu.; Department of Immunology, Duke University School of Medicine, Durham, NC, 27710, USA. barton.haynes@duke.edu.
Source: Nature communications [Nat Commun] 2022 Oct 23; Vol. 13 (1), pp. 6309. Date of Electronic Publication: 2022 Oct 23.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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