Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.

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Title: Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.
Authors: Yaron TM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Tri-Institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine/Memorial Sloan Kettering Cancer Center/Rockefeller University, New York, NY 10021, USA., Heaton BE; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Levy TM; Cell Signaling Technology, Danvers, MA 01923, USA., Johnson JL; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Jordan TX; Grossman School of Medicine, New York University, New York, NY 10016, USA., Cohen BM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Kerelsky A; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Lin TY; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., Liberatore KM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Bulaon DK; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Van Nest SJ; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY 10065, USA., Koundouros N; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA., Kastenhuber ER; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Mercadante MN; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Shobana-Ganesh K; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, NY 10065, USA., He L; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Schwartz RE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Chen S; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA., Weinstein H; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA., Elemento O; Englander Institute for Precision Medicine, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA., Piskounova E; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Dermatology, Weill Cornell Medicine, New York, NY 10065, USA., Nilsson-Payant BE; Grossman School of Medicine, New York University, New York, NY 10016, USA., Lee G; Department of Microbiology and Molecular Genetics, Chao Family Comprehensive Cancer Center, University of California, Irvine School of Medicine, Irvine, CA 92868, USA., Trimarco JD; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Burke KN; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Hamele CE; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Chaparian RR; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Harding AT; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Tata A; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Zhu X; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Tata PR; Department of Cell Biology, Duke University School of Medicine, Durham, NC 27710, USA., Smith CM; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Possemato AP; Cell Signaling Technology, Danvers, MA 01923, USA., Tkachev SL; Cell Signaling Technology, Danvers, MA 01923, USA., Hornbeck PV; Cell Signaling Technology, Danvers, MA 01923, USA., Beausoleil SA; Cell Signaling Technology, Danvers, MA 01923, USA., Anand SK; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Aguet F; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Getz G; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.; Cancer Center and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA., Davidson AD; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., Heesom K; Proteomics Facility, University of Bristol, Bristol BS8 1TD, UK., Kavanagh-Williamson M; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., Matthews DA; School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, UK., tenOever BR; Grossman School of Medicine, New York University, New York, NY 10016, USA., Cantley LC; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA., Blenis J; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA.; Department of Biochemistry, Weill Cornell Medicine, New York, NY 10065, USA., Heaton NS; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC 27710, USA.
Source: Science signaling [Sci Signal] 2022 Oct 25; Vol. 15 (757), pp. eabm0808. Date of Electronic Publication: 2022 Oct 25.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1937-9145
DOI:10.1126/scisignal.abm0808