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Safety, Tolerability, and Pharmacokinetics of Intravenous Doses of PF-07304814, a Phosphate Prodrug Protease Inhibitor for the Treatment of SARS-CoV-2, in Healthy Adult Participants.

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Title: Safety, Tolerability, and Pharmacokinetics of Intravenous Doses of PF-07304814, a Phosphate Prodrug Protease Inhibitor for the Treatment of SARS-CoV-2, in Healthy Adult Participants.
Authors: Zhu T; Pfizer Worldwide Research, Development and Medical, Cambridge, Massachusetts, USA., Pawlak S; Pfizer Clinical Research Unit, New Haven, Connecticut, USA., Toussi SS; Pfizer Worldwide Research, Development and Medical, Pearl River, New York, USA., Hackman F; Pfizer Worldwide Research, Development and Medical, Cambridge, UK., Thompson K; Pfizer Clinical Research Unit, New Haven, Connecticut, USA., Song W; Pfizer Worldwide Research, Development and Medical, Groton, Connecticut, USA., Salageanu J; Pfizer Global Product Development, Groton, Connecticut, USA., Winter E; Pfizer Global Product Development, Groton, Connecticut, USA., Shi H; Pfizer Global Product Development, Groton, Connecticut, USA., Winton J; Pfizer Global Product Development, Groton, Connecticut, USA., Binks M; Pfizer Worldwide Research, Development and Medical, Cambridge, Massachusetts, USA.
Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Dec; Vol. 11 (12), pp. 1382-1393. Date of Electronic Publication: 2022 Oct 26.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety, Tolerability, and Pharmacokinetics of Intravenous Doses of PF-07304814, a Phosphate Prodrug Protease Inhibitor for the Treatment of SARS-CoV-2, in Healthy Adult Participants.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+T%22">Zhu T</searchLink>; Pfizer Worldwide Research, Development and Medical, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Pawlak+S%22">Pawlak S</searchLink>; Pfizer Clinical Research Unit, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Toussi+SS%22">Toussi SS</searchLink>; Pfizer Worldwide Research, Development and Medical, Pearl River, New York, USA.<br /><searchLink fieldCode="AU" term="%22Hackman+F%22">Hackman F</searchLink>; Pfizer Worldwide Research, Development and Medical, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Thompson+K%22">Thompson K</searchLink>; Pfizer Clinical Research Unit, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Song+W%22">Song W</searchLink>; Pfizer Worldwide Research, Development and Medical, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Salageanu+J%22">Salageanu J</searchLink>; Pfizer Global Product Development, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Winter+E%22">Winter E</searchLink>; Pfizer Global Product Development, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Shi+H%22">Shi H</searchLink>; Pfizer Global Product Development, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Winton+J%22">Winton J</searchLink>; Pfizer Global Product Development, Groton, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Binks+M%22">Binks M</searchLink>; Pfizer Worldwide Research, Development and Medical, Cambridge, Massachusetts, USA.
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              Text: 2022 Dec
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