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BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.

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Title: BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.
Authors: Panditharatna E; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Marques JG; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Wang T; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Trissal MC; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Liu I; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Jiang L; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Beck A; Center for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany., Groves A; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Dharia NV; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Li D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Hoffman SE; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Kugener G; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Shaw ML; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts., Mire HM; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Hack OA; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts., Dempster JM; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Lareau C; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Pathology, Stanford University, Stanford, California., Dai L; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Sigua LH; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Quezada MA; Department of Neurology, Stanford University School of Medicine, Stanford, California., Stanton AJ; Department of Neurosurgery, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Wyatt M; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Kalani Z; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Goodale A; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Vazquez F; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Piccioni F; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Merck Research Laboratories, Cambridge, Massachusetts., Doench JG; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Root DE; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Anastas JN; Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts.; Department of Neurosurgery and Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas., Jones KL; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Conway AS; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts., Stopka S; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Regan MS; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Liang Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Seo HS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts., Song K; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Bashyal P; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Jerome WP; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts., Mathewson ND; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts.; Department of Microbiology and Immunobiology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts.; Department of Neurology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts., Dhe-Paganon S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts., Suvà ML; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Klarman Cell Observatory, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Carcaboso AM; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Lavarino C; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Mora J; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Nguyen QD; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Ligon KL; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Pathology, Boston Children's Hospital, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts., Shi Y; Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts.; Ludwig Institute for Cancer Research, Oxford Branch, Oxford University, Oxford, United Kingdom., Agnihotri S; Department of Neurosurgery, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Agar NYR; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Stegmaier K; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Stiles CD; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Monje M; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California., Golub TR; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts., Qi J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Filbin MG; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.
Source: Cancer discovery [Cancer Discov] 2022 Dec 02; Vol. 12 (12), pp. 2880-2905.
Publication Type: Editorial; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Comment
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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DbLabel: MEDLINE Ultimate
An: 36305736
AccessLevel: 2
PubType: Report
PubTypeId: report
PreciseRelevancyScore: 0
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  Data: BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.
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  Data: <searchLink fieldCode="AU" term="%22Panditharatna+E%22">Panditharatna E</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Marques+JG%22">Marques JG</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Trissal+MC%22">Trissal MC</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; 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Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Dharia+NV%22">Dharia NV</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hoffman+SE%22">Hoffman SE</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Kugener+G%22">Kugener G</searchLink>; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Shaw+ML%22">Shaw ML</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Mire+HM%22">Mire HM</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Hack+OA%22">Hack OA</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Dempster+JM%22">Dempster JM</searchLink>; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Lareau+C%22">Lareau C</searchLink>; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Pathology, Stanford University, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Dai+L%22">Dai L</searchLink>; 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Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts.; Department of Neurosurgery and Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Jones+KL%22">Jones KL</searchLink>; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Conway+AS%22">Conway AS</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Stopka+S%22">Stopka S</searchLink>; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Regan+MS%22">Regan MS</searchLink>; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Seo+HS%22">Seo HS</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Song+K%22">Song K</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Bashyal+P%22">Bashyal P</searchLink>; 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Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Suvà+ML%22">Suvà ML</searchLink>; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.; Klarman Cell Observatory, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Carcaboso+AM%22">Carcaboso AM</searchLink>; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Lavarino+C%22">Lavarino C</searchLink>; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mora+J%22">Mora J</searchLink>; Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Nguyen+QD%22">Nguyen QD</searchLink>; Lurie Family Imaging Center, Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Ligon+KL%22">Ligon KL</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.; Department of Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Pathology, Boston Children's Hospital, Boston, Massachusetts.; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Division of Newborn Medicine and Epigenetics Program, Department of Medicine, Boston Children's Hospital, Boston, Massachusetts.; Ludwig Institute for Cancer Research, Oxford Branch, Oxford University, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Agnihotri+S%22">Agnihotri S</searchLink>; Department of Neurosurgery, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Agar+NYR%22">Agar NYR</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Stegmaier+K%22">Stegmaier K</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Stiles+CD%22">Stiles CD</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Monje+M%22">Monje M</searchLink>; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Golub+TR%22">Golub TR</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Qi+J%22">Qi J</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Filbin+MG%22">Filbin MG</searchLink>; Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, Massachusetts.; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts.
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          Name:
            NameFull: Suvà ML
      – PersonEntity:
          Name:
            NameFull: Carcaboso AM
      – PersonEntity:
          Name:
            NameFull: Lavarino C
      – PersonEntity:
          Name:
            NameFull: Mora J
      – PersonEntity:
          Name:
            NameFull: Nguyen QD
      – PersonEntity:
          Name:
            NameFull: Ligon KL
      – PersonEntity:
          Name:
            NameFull: Shi Y
      – PersonEntity:
          Name:
            NameFull: Agnihotri S
      – PersonEntity:
          Name:
            NameFull: Agar NYR
      – PersonEntity:
          Name:
            NameFull: Stegmaier K
      – PersonEntity:
          Name:
            NameFull: Stiles CD
      – PersonEntity:
          Name:
            NameFull: Monje M
      – PersonEntity:
          Name:
            NameFull: Golub TR
      – PersonEntity:
          Name:
            NameFull: Qi J
      – PersonEntity:
          Name:
            NameFull: Filbin MG
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 12
              Text: 2022 Dec 02
              Type: published
              Y: 2022
          Identifiers:
            – Type: issn-electronic
              Value: 2159-8290
          Numbering:
            – Type: volume
              Value: 12
            – Type: issue
              Value: 12
          Titles:
            – TitleFull: Cancer discovery
              Type: main
ResultId 1