Randomized trial of bilateral gene therapy injection for m.11778G>A MT-ND4 Leber optic neuropathy.
Saved in:
| Title: | Randomized trial of bilateral gene therapy injection for m.11778G>A MT-ND4 Leber optic neuropathy. |
|---|---|
| Authors: | Newman NJ; Departments of Ophthalmology, Neurology and Neurological Surgery, Emory University School of Medicine, Atlanta, GA, USA., Yu-Wai-Man P; Cambridge Centre for Brain Repair and MRC Mitochondrial Biology Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cambridge Eye Unit, Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, UK.; Moorfields Eye Hospital, London, UK.; UCL Institute of Ophthalmology, University College London, London, UK., Subramanian PS; Sue Anschutz-Rodgers University of Colorado Eye Center, University of Colorado School of Medicine, Aurora, CO, USA., Moster ML; Departments of Neurology and Ophthalmology, Wills Eye Hospital and Thomas Jefferson University, Philadelphia, PA, USA., Wang AG; Department of Ophthalmology, Taipei Veterans General Hospital, National Yang Ming Chiao Tung University, Taipei, Taiwan., Donahue SP; Department of Ophthalmology, Neurology, and Pediatrics, Vanderbilt University, and Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Leroy BP; Department of Ophthalmology and Center for Medical Genetics, Ghent University Hospital, and Department of Head & Skin, Ghent University, Ghent, Belgium., Carelli V; IRCCS Istituto delle Scienze Neurologiche di Bologna, Programma di Neurogenetica, Bologna, Italy.; Unit of Neurology, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Biousse V; Departments of Ophthalmology, Neurology and Neurological Surgery, Emory University School of Medicine, Atlanta, GA, USA., Vignal-Clermont C; Department of Neuro Ophthalmology and Emergencies, Rothschild Foundation Hospital, Paris, France.; Department of Ophthalmology, Centre Hospitalier National D'Ophtalmologie des Quinze Vingts, Paris, France., Sergott RC; Departments of Neurology and Ophthalmology, Wills Eye Hospital and Thomas Jefferson University, Philadelphia, PA, USA., Sadun AA; Doheny Eye Institute, UCLA School of Medicine, Los Angeles, CA, USA., Rebolleda Fernández G; Department of Ophthalmology, Alcala University, Madrid, Spain., Chwalisz BK; Department of Ophthalmology, Massachusetts Eye & Ear, Harvard Medical School, Boston, MA, USA.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Banik R; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bazin F; eXYSTAT, Data Management and Statistics, Paris, France., Roux M; GenSight Biologics, Paris, France., Cox ED; GenSight Biologics, Paris, France., Taiel M; GenSight Biologics, Paris, France., Sahel JA; Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.; Fondation Ophtalmologique A. de Rothschild, Paris, France.; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; CHNO des Quinze-Vingts, Institut Hospitalo-Universitaire FOReSIGHT, INSERM-DGOS CIC, Paris, France. |
| Corporate Authors: | LHON REFLECT Study Group |
| Source: | Brain : a journal of neurology [Brain] 2023 Apr 19; Vol. 146 (4), pp. 1328-1341. |
| Publication Type: | Randomized Controlled Trial; Clinical Trial, Phase III; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1460-2156 |
|---|---|
| DOI: | 10.1093/brain/awac421 |
