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Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia.

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Title: Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia.
Authors: Schrottmaier WC; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Kral-Pointner JB; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Salzmann M; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Mussbacher M; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria; Department of Pharmacology and Toxicology, Institute of Pharmaceutical Sciences, University of Graz, 8010 Graz, Austria., Schmuckenschlager A; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Pirabe A; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Brunnthaler L; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Kuttke M; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Maier B; Department of Medicine I, Research Division of Infection Biology, Medical University Vienna, 1090 Vienna, Austria., Heber S; Institute of Physiology, Centre for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria., Datler H; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Ekici Y; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria., Niederreiter B; Division of Rheumatology, Internal Medicine III, Medical University of Vienna, 1090 Vienna, Austria., Heber U; Department of Pathology and Comprehensive Cancer Centre, Medical University of Vienna, 1090 Vienna, Austria., Blomgren B; Department of Clinical Sciences, Danderyd Hospital, Department of Oncology-Pathology, Karolinska Institutet, 171 77 Stockholm, Sweden., Gorki AD; Department of Medicine I, Research Division of Infection Biology, Medical University Vienna, 1090 Vienna, Austria., Söderberg-Nauclér C; Department of Medicine, Solna, Centre for Molecular Medicine, Microbial Pathogenesis Unit, Karolinska University Hospital, Karolinska Institutet, 17177 Stockholm, Sweden., Payrastre B; INSERM UMR1297, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III Paul Sabatier, 31024 Toulouse, France., Gratacap MP; INSERM UMR1297, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III Paul Sabatier, 31024 Toulouse, France., Knapp S; Department of Medicine I, Research Division of Infection Biology, Medical University Vienna, 1090 Vienna, Austria., Schabbauer G; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria. Electronic address: gernot.schabbauer@meduniwien.ac.at., Assinger A; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria. Electronic address: alice.assinger@meduniwien.ac.at.
Source: Cell reports [Cell Rep] 2022 Nov 08; Vol. 41 (6), pp. 111614.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: Platelet p110β mediates platelet-leukocyte interaction and curtails bacterial dissemination in pneumococcal pneumonia.
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  Data: <searchLink fieldCode="AU" term="%22Schrottmaier+WC%22">Schrottmaier WC</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Kral-Pointner+JB%22">Kral-Pointner JB</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Salzmann+M%22">Salzmann M</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Mussbacher+M%22">Mussbacher M</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria; Department of Pharmacology and Toxicology, Institute of Pharmaceutical Sciences, University of Graz, 8010 Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Schmuckenschlager+A%22">Schmuckenschlager A</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Pirabe+A%22">Pirabe A</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Brunnthaler+L%22">Brunnthaler L</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Kuttke+M%22">Kuttke M</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Maier+B%22">Maier B</searchLink>; Department of Medicine I, Research Division of Infection Biology, Medical University Vienna, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Heber+S%22">Heber S</searchLink>; Institute of Physiology, Centre for Physiology and Pharmacology, Medical University of Vienna, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Datler+H%22">Datler H</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ekici+Y%22">Ekici Y</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Niederreiter+B%22">Niederreiter B</searchLink>; Division of Rheumatology, Internal Medicine III, Medical University of Vienna, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Heber+U%22">Heber U</searchLink>; Department of Pathology and Comprehensive Cancer Centre, Medical University of Vienna, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Blomgren+B%22">Blomgren B</searchLink>; Department of Clinical Sciences, Danderyd Hospital, Department of Oncology-Pathology, Karolinska Institutet, 171 77 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Gorki+AD%22">Gorki AD</searchLink>; Department of Medicine I, Research Division of Infection Biology, Medical University Vienna, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Söderberg-Nauclér+C%22">Söderberg-Nauclér C</searchLink>; Department of Medicine, Solna, Centre for Molecular Medicine, Microbial Pathogenesis Unit, Karolinska University Hospital, Karolinska Institutet, 17177 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Payrastre+B%22">Payrastre B</searchLink>; INSERM UMR1297, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III Paul Sabatier, 31024 Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Gratacap+MP%22">Gratacap MP</searchLink>; INSERM UMR1297, Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Toulouse III Paul Sabatier, 31024 Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Knapp+S%22">Knapp S</searchLink>; Department of Medicine I, Research Division of Infection Biology, Medical University Vienna, 1090 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schabbauer+G%22">Schabbauer G</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria. Electronic address: gernot.schabbauer@meduniwien.ac.at.<br /><searchLink fieldCode="AU" term="%22Assinger+A%22">Assinger A</searchLink>; Department of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstraße 17, 1090 Vienna, Austria. Electronic address: alice.assinger@meduniwien.ac.at.
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