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Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits.

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Title: Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits.
Authors: Nguyen HTM; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; Department of Biochemistry, Hanoi University of Pharmacy, Hanoi, Vietnam., van der Westhuizen ET; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia., Langmead CJ; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; Neuromedicines Discovery Centre, Monash University, Parkville, Melbourne, VIC, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash University, Parkville, Melbourne, VIC, Australia., Tobin AB; Centre for Translational Pharmacology, University of Glasgow, Glasgow, UK., Sexton PM; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash University, Parkville, Melbourne, VIC, Australia., Christopoulos A; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; Neuromedicines Discovery Centre, Monash University, Parkville, Melbourne, VIC, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash University, Parkville, Melbourne, VIC, Australia., Valant C; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; Neuromedicines Discovery Centre, Monash University, Parkville, Melbourne, VIC, Australia.
Source: British journal of pharmacology [Br J Pharmacol] 2024 Jul; Vol. 181 (14), pp. 2114-2142. Date of Electronic Publication: 2022 Dec 04.
Publication Type: Journal Article; Review
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Opportunities and challenges for the development of M<subscript>1</subscript> muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+HTM%22">Nguyen HTM</searchLink>; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; Department of Biochemistry, Hanoi University of Pharmacy, Hanoi, Vietnam.<br /><searchLink fieldCode="AU" term="%22van+der+Westhuizen+ET%22">van der Westhuizen ET</searchLink>; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Langmead+CJ%22">Langmead CJ</searchLink>; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; Neuromedicines Discovery Centre, Monash University, Parkville, Melbourne, VIC, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash University, Parkville, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Tobin+AB%22">Tobin AB</searchLink>; Centre for Translational Pharmacology, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Sexton+PM%22">Sexton PM</searchLink>; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash University, Parkville, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Christopoulos+A%22">Christopoulos A</searchLink>; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; Neuromedicines Discovery Centre, Monash University, Parkville, Melbourne, VIC, Australia.; ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash University, Parkville, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Valant+C%22">Valant C</searchLink>; Drug Discovery Biology, Monash University, Parkville, Melbourne, VIC, Australia.; Neuromedicines Discovery Centre, Monash University, Parkville, Melbourne, VIC, Australia.
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              Text: 2024 Jul
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