APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression.
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| Title: | APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression. |
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| Authors: | Dincer A; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Chen CD; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., McKay NS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Koenig LN; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., McCullough A; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Flores S; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Keefe SJ; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Schultz SA; Massachusetts General Hospital, Boston, MA 02114, USA., Feldman RL; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Joseph-Mathurin N; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Hornbeck RC; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Cruchaga C; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO 63110, USA., Schindler SE; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Holtzman DM; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA., Morris JC; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Fagan AM; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Benzinger TLS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Gordon BA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Psychological and Brain Sciences, Washington University, Saint Louis, MO 63110, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2022 Nov 16; Vol. 14 (671), pp. eabl7646. Date of Electronic Publication: 2022 Nov 16. |
| Publication Type: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.abl7646 |
