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APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression.

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Title: APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression.
Authors: Dincer A; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Chen CD; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., McKay NS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Koenig LN; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., McCullough A; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Flores S; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Keefe SJ; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Schultz SA; Massachusetts General Hospital, Boston, MA 02114, USA., Feldman RL; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Joseph-Mathurin N; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Hornbeck RC; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Cruchaga C; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO 63110, USA., Schindler SE; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Holtzman DM; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA., Morris JC; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Fagan AM; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Benzinger TLS; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA., Gordon BA; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Psychological and Brain Sciences, Washington University, Saint Louis, MO 63110, USA.
Source: Science translational medicine [Sci Transl Med] 2022 Nov 16; Vol. 14 (671), pp. eabl7646. Date of Electronic Publication: 2022 Nov 16.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: APOE ε4 genotype, amyloid-β, and sex interact to predict tau in regions of high APOE mRNA expression.
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  Data: <searchLink fieldCode="AU" term="%22Dincer+A%22">Dincer A</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Chen+CD%22">Chen CD</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22McKay+NS%22">McKay NS</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Koenig+LN%22">Koenig LN</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22McCullough+A%22">McCullough A</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Flores+S%22">Flores S</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Keefe+SJ%22">Keefe SJ</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Schultz+SA%22">Schultz SA</searchLink>; Massachusetts General Hospital, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Feldman+RL%22">Feldman RL</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Joseph-Mathurin+N%22">Joseph-Mathurin N</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Hornbeck+RC%22">Hornbeck RC</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Schindler+SE%22">Schindler SE</searchLink>; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Holtzman+DM%22">Holtzman DM</searchLink>; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Morris+JC%22">Morris JC</searchLink>; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Fagan+AM%22">Fagan AM</searchLink>; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Benzinger+TLS%22">Benzinger TLS</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+BA%22">Gordon BA</searchLink>; Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Knight Alzheimer Disease Research Center, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, Saint Louis, MO 63110, USA.; Department of Psychological and Brain Sciences, Washington University, Saint Louis, MO 63110, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2022 Nov 16; Vol. 14 (671), pp. eabl7646. <i>Date of Electronic Publication: </i>2022 Nov 16.
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