Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex.

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Title: Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex.
Authors: McNamara MC; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Hosios AM; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Torrence ME; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA., Zhao T; Department of Urology, Massachusetts General Hospital, Boston, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Fraser C; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02215, USA., Wilkinson M; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Kwiatkowski DJ; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Henske EP; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Wu CL; Department of Urology, Massachusetts General Hospital, Boston, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Sarosiek KA; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02215, USA., Valvezan AJ; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA., Manning BD; Department of Molecular Metabolism, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Source: IScience [iScience] 2022 Oct 28; Vol. 25 (11), pp. 105458. Date of Electronic Publication: 2022 Oct 28 (Print Publication: 2022).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2589-0042
DOI:10.1016/j.isci.2022.105458