LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus.
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| Title: | LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus. |
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| Authors: | Wu Z; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Berlemann LA; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Bader V; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany.; Department Biochemistry of Neurodegenerative Diseases, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Sehr DA; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Dawin E; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany.; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V, Dortmund, Germany., Covallero A; Department of Biomedical Sciences, University of Padua, Padua, Italy., Meschede J; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Angersbach L; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Showkat C; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Michaelis JB; Faculty of Medicine, Institute of Biochemistry II, Goethe University Frankfurt, Frankfurt am Main, Germany., Münch C; Faculty of Medicine, Institute of Biochemistry II, Goethe University Frankfurt, Frankfurt am Main, Germany., Rieger B; Institute for Integrative Cell Biology and Physiology, Faculty of Biology, University of Münster, Münster, Germany., Namgaladze D; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany., Herrera MG; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany., Fiesel FC; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Springer W; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA., Mendes M; Proteomics of Cellular Signaling, Department of Infection and Immunity, Luxembourg Institute of Health, Strassen, Luxembourg., Stepien J; Medizinisches Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany.; Medical Proteome Analysis, Center for Protein Diagnostics (PRODI), Ruhr-University Bochum, Bochum, Germany., Barkovits K; Medizinisches Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany.; Medical Proteome Analysis, Center for Protein Diagnostics (PRODI), Ruhr-University Bochum, Bochum, Germany., Marcus K; Medizinisches Proteom-Center, Ruhr-Universität Bochum, Bochum, Germany.; Medical Proteome Analysis, Center for Protein Diagnostics (PRODI), Ruhr-University Bochum, Bochum, Germany., Sickmann A; Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V, Dortmund, Germany., Dittmar G; Proteomics of Cellular Signaling, Department of Infection and Immunity, Luxembourg Institute of Health, Strassen, Luxembourg.; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux, Luxembourg., Busch KB; Institute for Integrative Cell Biology and Physiology, Faculty of Biology, University of Münster, Münster, Germany., Riedel D; Laboratory for Electron Microscopy, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany., Brini M; Department of Biology, University of Padua, Padua, Italy.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padua, Italy., Tatzelt J; Department Biochemistry of Neurodegenerative Diseases, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany.; RESOLV Cluster of Excellence, Ruhr University Bochum, Bochum, Germany., Cali T; Department of Biomedical Sciences, University of Padua, Padua, Italy.; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padua, Italy.; Padua Neuroscience Center (PNC), University of Padua, Padua, Italy., Winklhofer KF; Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum, Germany.; RESOLV Cluster of Excellence, Ruhr University Bochum, Bochum, Germany. |
| Source: | The EMBO journal [EMBO J] 2022 Dec 15; Vol. 41 (24), pp. e112006. Date of Electronic Publication: 2022 Nov 18. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.15252/embj.2022112006 |
