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An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma.

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Title: An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma.
Authors: Darawshi O; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Muz B; Department of Radiation Oncology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA., Naamat SG; Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel., Praveen B; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Mahameed M; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Goldberg K; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Dipta P; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Shmuel M; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Forno F; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Boukeileh S; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Pahima H; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel., Hermann J; German Cancer Research Center (DKFZ), Heidelberg, Germany., Raab MS; Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany., Poos AM; Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany., Weinhold N; Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany., Rosenbluh C; Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel., Gatt ME; Hematology Dept. Hadassah Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel., Palm W; German Cancer Research Center (DKFZ), Heidelberg, Germany., Azab AK; Department Biomedical Engineering, UT Southwestern, Dallas, TX, USA., Tirosh B; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel. boazt@ekmd.huji.ac.il.; Case Western Reserve University, Department of Biochemistry, Cleveland, OH, USA. boazt@ekmd.huji.ac.il.
Source: Cell death & disease [Cell Death Dis] 2022 Nov 18; Vol. 13 (11), pp. 969. Date of Electronic Publication: 2022 Nov 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma.
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  Data: <searchLink fieldCode="AU" term="%22Darawshi+O%22">Darawshi O</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Muz+B%22">Muz B</searchLink>; Department of Radiation Oncology, Washington University in St. Louis School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Naamat+SG%22">Naamat SG</searchLink>; Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Praveen+B%22">Praveen B</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Mahameed+M%22">Mahameed M</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Goldberg+K%22">Goldberg K</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Dipta+P%22">Dipta P</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Shmuel+M%22">Shmuel M</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Forno+F%22">Forno F</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Boukeileh+S%22">Boukeileh S</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Pahima+H%22">Pahima H</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Hermann+J%22">Hermann J</searchLink>; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Raab+MS%22">Raab MS</searchLink>; Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Poos+AM%22">Poos AM</searchLink>; Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Weinhold+N%22">Weinhold N</searchLink>; Department of Internal Medicine V, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Rosenbluh+C%22">Rosenbluh C</searchLink>; Department of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Gatt+ME%22">Gatt ME</searchLink>; Hematology Dept. Hadassah Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Palm+W%22">Palm W</searchLink>; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Azab+AK%22">Azab AK</searchLink>; Department Biomedical Engineering, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tirosh+B%22">Tirosh B</searchLink>; Institute for Drug Research, The Hebrew University of Jerusalem, Jerusalem, Israel. boazt@ekmd.huji.ac.il.; Case Western Reserve University, Department of Biochemistry, Cleveland, OH, USA. boazt@ekmd.huji.ac.il.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2022 Nov 18; Vol. 13 (11), pp. 969. <i>Date of Electronic Publication: </i>2022 Nov 18.
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