Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo.

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Title: Hyaluronan nanoscale clustering and Hyaluronan synthase 2 expression are linked to the invasion of child fibroblasts and infantile fibrosarcoma in vitro and in vivo.
Authors: Tonge JJ; Academic Unit of Medical Education, The Medical School, The University of Sheffield, Sheffield, UK.; Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK., Notley SV; Department of Automatic Control and Systems Engineering, The University of Sheffield, Sheffield, UK., Dunning MJ; Bioinformatics Core, The Medical School, The University of Sheffield, Sheffield, UK., López-Guajardo A; Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK., Medcalf JD; Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK., Heldin P; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden., Panoutsos G; Department of Automatic Control and Systems Engineering, The University of Sheffield, Sheffield, UK., Gad AKB; Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK. a.k.gad@sheffield.ac.uk.; Centro de Química da Madeira, Universidade da Madeira, Funchal, Portugal. a.k.gad@sheffield.ac.uk.
Source: Scientific reports [Sci Rep] 2022 Nov 18; Vol. 12 (1), pp. 19835. Date of Electronic Publication: 2022 Nov 18.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-022-21952-4