MEK inhibitor resistance in lung adenocarcinoma is associated with addiction to sustained ERK suppression.
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| Title: | MEK inhibitor resistance in lung adenocarcinoma is associated with addiction to sustained ERK suppression. |
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| Authors: | Farnsworth DA; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, Canada., Inoue Y; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, Canada., Johnson FD; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, Canada., de Rappard-Yuswack G; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, Canada., Lu D; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, Canada., Shi R; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, Canada., Ma LIJ; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, Canada., Mattar MS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Somwar R; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ladanyi M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Unni AM; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Lockwood WW; Department of Integrative Oncology, BC Cancer Research Institute, Vancouver, Canada. wlockwood@bccrc.ca.; Department of Pathology & Laboratory Medicine, University of British Columbia, Vancouver, Canada. wlockwood@bccrc.ca. |
| Source: | NPJ precision oncology [NPJ Precis Oncol] 2022 Nov 23; Vol. 6 (1), pp. 88. Date of Electronic Publication: 2022 Nov 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2397-768X |
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| DOI: | 10.1038/s41698-022-00328-x |
