Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.
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| Title: | Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma. |
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| Authors: | Kameda-Smith MM; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada.; Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada., Zhu H; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; University Health Network, Toronto, ON, Canada.; Vector Institute Toronto, Toronto, ON, Canada., Luo EC; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA., Suk Y; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada.; Michael G DeGroote School of Medicine, McMaster University, Hamilton, Canada., Xella A; Tumor Initiation and Maintenance Program, National Cancer Institute-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Yee B; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA., Chokshi C; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Xing S; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Tan F; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.; Stem Cell Program, University of California San Diego, La Jolla, CA, USA.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA., Fox RG; Departments of Pharmacology and Medicine, University of California San Diego School of Medicine, Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA., Adile AA; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Bakhshinyan D; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Brown K; Donnelly Centre, Department of Molecular Genetics, University of Toronto, Toronto, Canada., Gwynne WD; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Subapanditha M; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada., Miletic P; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Picard D; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, University Hospital Düsseldorf, Düsseldorf, Germany., Burns I; Michael G DeGroote School of Medicine, McMaster University, Hamilton, Canada., Moffat J; Donnelly Centre, Department of Molecular Genetics, University of Toronto, Toronto, Canada., Paruch K; Department of Chemistry, CZ Openscreen, Faculty of Science, Masaryk University, Kamenice 5, 625 00, Brno, Czech Republic.; International Clinical Research Center, St. Anne's University Hospital in Brno, 602 00, Brno, Czech Republic., Fleming A; McMaster University, Departments of Pediatrics, Hematology and Oncology Division, Hamilton, Canada., Hope K; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Provias JP; McMaster University, Departments of Neuropathology, Hamilton, Canada., Remke M; Department of Pediatric Oncology, Hematology, and Clinical Immunology, Medical Faculty, University Hospital Düsseldorf, Düsseldorf, Germany., Lu Y; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada., Reya T; Departments of Pharmacology and Medicine, University of California San Diego School of Medicine, Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA.; Herbert Irving Comprehensive Cancer Center, Department of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY, USA., Venugopal C; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada.; Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada., Reimand J; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Canada., Wechsler-Reya RJ; Tumor Initiation and Maintenance Program, National Cancer Institute-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. rjw2169@cumc.columbia.edu.; Herbert Irving Comprehensive Cancer Center, Department of Physiology and Cellular Biophysics, Columbia University Medical Center, New York, NY, USA. rjw2169@cumc.columbia.edu., Yeo GW; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA. geneyeo@ucsd.edu.; Stem Cell Program, University of California San Diego, La Jolla, CA, USA. geneyeo@ucsd.edu.; Sanford Consortium for Regenerative Medicine, La Jolla, CA, USA. geneyeo@ucsd.edu., Singh SK; Centre for Discovery in Cancer Research (CDCR), McMaster University, Hamilton, ON, Canada. ssingh@mcmaster.ca.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada. ssingh@mcmaster.ca.; Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada. ssingh@mcmaster.ca.; McMaster University, Department of Pediatrics, Hamilton, Canada. ssingh@mcmaster.ca. |
| Source: | Nature communications [Nat Commun] 2022 Dec 06; Vol. 13 (1), pp. 7506. Date of Electronic Publication: 2022 Dec 06. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-022-35118-3 |
