Apilimod enhances specific productivity in recombinant CHO cells through cell cycle arrest and mediation of autophagy.
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| Title: | Apilimod enhances specific productivity in recombinant CHO cells through cell cycle arrest and mediation of autophagy. |
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| Authors: | Lu JT; School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan, China.; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, Henan, China.; Henan Engineering Research Center for Biopharmaceutical Innovation, Xinxiang Medical University, Xinxiang, Henan, China., Xiao MK; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, Henan, China.; Henan Engineering Research Center for Biopharmaceutical Innovation, Xinxiang Medical University, Xinxiang, Henan, China.; School of Public Health, Xinxiang Medical University, Xinxiang, Henan, China., Feng YY; School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan, China.; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, Henan, China.; Henan Engineering Research Center for Biopharmaceutical Innovation, Xinxiang Medical University, Xinxiang, Henan, China., Wang XY; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, Henan, China.; Henan Engineering Research Center for Biopharmaceutical Innovation, Xinxiang Medical University, Xinxiang, Henan, China.; School of Basic Medicine, Xinxiang Medical University, Xinxiang, Henan, China., Qiu LL; School of Basic Medicine, Xinxiang Medical University, Xinxiang, Henan, China., Chai YR; Department of Histology and Embryology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China., Wang TY; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, Henan, China.; Henan Engineering Research Center for Biopharmaceutical Innovation, Xinxiang Medical University, Xinxiang, Henan, China.; School of Basic Medicine, Xinxiang Medical University, Xinxiang, Henan, China., Jia YL; School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan, China.; International Joint Research Laboratory for Recombinant Pharmaceutical Protein Expression System of Henan, Xinxiang Medical University, Xinxiang, Henan, China.; Henan Engineering Research Center for Biopharmaceutical Innovation, Xinxiang Medical University, Xinxiang, Henan, China. |
| Source: | Biotechnology journal [Biotechnol J] 2023 Feb; Vol. 18 (2), pp. e2200147. Date of Electronic Publication: 2022 Dec 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101265833 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7314 (Electronic) Linking ISSN: 18606768 NLM ISO Abbreviation: Biotechnol J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1860-7314 |
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| DOI: | 10.1002/biot.202200147 |
