The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi.

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Title: The establishment of COPD organoids to study host-pathogen interaction reveals enhanced viral fitness of SARS-CoV-2 in bronchi.
Authors: Chan LLY; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. louisa.chanly@ntu.edu.sg., Anderson DE; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Cheng HS; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Ivan FX; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Chen S; School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore., Kang AEZ; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Foo R; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Gamage AM; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Tiew PY; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Koh MS; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Lee KCH; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Nichol K; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia., Pathinayake PS; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia., Chan YL; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia., Yeo TW; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases, Singapore, Singapore., Oliver BG; School of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW, Australia.; Woolcock Institute of Medical Research, The University of Sydney, Sydney, NSW, Australia., Wark PAB; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.; Department of Respiratory and Sleep Medicine, John Hunter Hospital, New Lambton Heights, NSW, Australia., Liu L; School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore, Singapore.; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore, Singapore., Tan NS; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Wang LF; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.; Singhealth Duke-NUS Global Health Institute, Singapore, Singapore., Chotirmall SH; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. schotirmall@ntu.edu.sg.; Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore, Singapore. schotirmall@ntu.edu.sg.
Source: Nature communications [Nat Commun] 2022 Dec 10; Vol. 13 (1), pp. 7635. Date of Electronic Publication: 2022 Dec 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-022-35253-x